A Prospective Study to Evaluate the Prevalence of Bacterial Profile and its Antibiogram

Background: The bacterial profile and the antibiotic pattern of the wound infections may change from time to time and place to place. Emergence of antimicrobial drug resistance has made the treatment of these wound infections very difficult. Aim: The aim of the study was to identify the prevalent bacterial profile and its antibiogram in our area. Materials and Methods: Pus samples from various sites were collected aseptically from 828 patients and were subjected to isolation and identification of aerobic bacteria by standard technique and subsequently antibiogram was carried out by Kirby-Bauer method. Results: Of the 828 clinical samples, 458 showed growth. Staphylococcus aureus was the most common organism isolated (37%), followed by Escherichia coli (21%), Klebsiella (17%), Pseudomonas (8%) among others. S. aureus was found to be highly resistant to penicillin, ampicillin, and erythromycin, while being sensitive to linezolid and vancomycin. On the other hand, of the gram-negative bacilli isolated, E. coli was found to be more common, followed by Klebsiella, Pseudomonas, Proteus, and Acinetobacter. They were all found to be highly resistant to cephalosporins and fairly sensitive to aminoglycosides and carbapenems. Conclusion: This study shows that in spite of the topographical diversity, the infecting bacterial isolates and their antibiogram from this area are found to be similar to those found in any other part of India