International audienceThe K4 peptide (KKKKPLFGLFFGLF) was recently demonstrated to display good antimicrobial activities against various bacterial strains and thus represents a candidate for the treatment of multiple-drug resistant infections. In this study, we use various techniques to study K4 behaviour in different media: water, solutions of detergent micelles, phospholipid monolayers and suspension of phospholipid vesicles. First, self-assembly of the peptide in water is observed, leading to the formation of spherical objects around 10nm in diameter. The addition of micelles induces partial peptide folding to an extent depending on the charge of the detergent headgroups. The NMR structure of the peptide in the presence of SDS displays a...
AbstractCationic antimicrobial peptides (CAMPs) selectively target bacterial membranes by electrosta...
Essential understanding : Elucidation of structural requirements and interactions of antimicrobial p...
Antimicrobial peptides (AMPs) are important components of the host innate defense mechanism against ...
De novo antimicrobial peptides were designed to help study the necessary conformational properties o...
International audienceWith 14 residues organized as two domains linked by a single proline, the de n...
AbstractAntimicrobial peptides have raised much interest as pathogens become resistant against conve...
In recent years, interest has grown in the antimicrobial properties of certain natural and non-natur...
With rising disease rates and decreasing effectiveness of conventional antibiotics, there is an imme...
Antimicrobial peptides (AMPs) are important components of the host innate defense mechanism against ...
The self-assembly behavior and antimicrobial activity of two designed amphiphilic peptides, R3F3 and...
The accumulation of bacteria on surfaces is currently one of the greatest concerns f or the supply ...
Cationic antimicrobial peptides (CAMPs) are a promising alternative to treat multidrug-resistant bac...
Antimicrobial cationic peptides are ubiquitous in nature and are thought to be a component of the f...
The activity of antimicrobial peptides stems from their interaction with bacterial membranes, which ...
In recent years, strains of bacteria with resistance to conventional antibiotics have been emerging ...
AbstractCationic antimicrobial peptides (CAMPs) selectively target bacterial membranes by electrosta...
Essential understanding : Elucidation of structural requirements and interactions of antimicrobial p...
Antimicrobial peptides (AMPs) are important components of the host innate defense mechanism against ...
De novo antimicrobial peptides were designed to help study the necessary conformational properties o...
International audienceWith 14 residues organized as two domains linked by a single proline, the de n...
AbstractAntimicrobial peptides have raised much interest as pathogens become resistant against conve...
In recent years, interest has grown in the antimicrobial properties of certain natural and non-natur...
With rising disease rates and decreasing effectiveness of conventional antibiotics, there is an imme...
Antimicrobial peptides (AMPs) are important components of the host innate defense mechanism against ...
The self-assembly behavior and antimicrobial activity of two designed amphiphilic peptides, R3F3 and...
The accumulation of bacteria on surfaces is currently one of the greatest concerns f or the supply ...
Cationic antimicrobial peptides (CAMPs) are a promising alternative to treat multidrug-resistant bac...
Antimicrobial cationic peptides are ubiquitous in nature and are thought to be a component of the f...
The activity of antimicrobial peptides stems from their interaction with bacterial membranes, which ...
In recent years, strains of bacteria with resistance to conventional antibiotics have been emerging ...
AbstractCationic antimicrobial peptides (CAMPs) selectively target bacterial membranes by electrosta...
Essential understanding : Elucidation of structural requirements and interactions of antimicrobial p...
Antimicrobial peptides (AMPs) are important components of the host innate defense mechanism against ...