While Salmonella enterica is seen as an archetypal facultative intracellular bacterial pathogen where protection is mediated by CD4+ T cells, identifying circulating protective cells has proved very difficult, inhibiting steps to identify key antigen specificities. Exploiting a mouse model of vaccination, we show that the spleens of C57BL/6 mice vaccinated with live-attenuated Salmonella serovar Typhimurium (S. Typhimurium) strains carried a pool of IFN-γ+ CD4+ T cells that could adoptively transfer protection, but only transiently. Circulating Salmonella-reactive CD4+ T cells expressed the liver-homing chemokine receptor CXCR6, accumulated over time in the liver and assumed phenotypic characteristics associated with tissue-associated T cel...
In this Pivotal Advance manuscript, the authors address the “paradox of Salmonella immunity and immu...
<div><p>Invasive <em>Salmonella</em> infection is an important health problem that is worsening beca...
Infection with Salmonella enterica serovar Typhimurium (S. Typhimurium) causes a severe and lethal s...
While Salmonella enterica is seen as an archetypal facultative intracellular bacterial pathogen wher...
While Salmonella enterica is seen as an archetypal facultative intracellular bacterial pathogen wher...
© 2017 Dr. Newton Gil PeresBacterial infections that are chiefly caused by food or water contaminate...
Salmonella typhi is the causative organism for typhoid fever, a serious systemic disease in humans. ...
AbstractA novel adoptive transfer system was used to track the fate of naive Salmonella-specific CD4...
While CD4 Th1 cells are required for resistance to intramacrophage infections, adoptive transfer of ...
Invasive Salmonella infection is an important health problem that is worsening because of rising ant...
Invasive Salmonella infection is an important health problem that is worsening because of rising ant...
<div><p><em>Salmonella enterica</em> serovars are intracellular bacteria capable of causing typhoid ...
niversity of Minnesota Ph.D. dissertation. October 2010. Major: Microbiology, Immunology and Cancer ...
AbstractSuccessful immunity against Salmonella infections is dependent on the generation of CD4+ T h...
Salmonella enterica serovars are intracellular bacteria capable of causing typhoid fever and gastroe...
In this Pivotal Advance manuscript, the authors address the “paradox of Salmonella immunity and immu...
<div><p>Invasive <em>Salmonella</em> infection is an important health problem that is worsening beca...
Infection with Salmonella enterica serovar Typhimurium (S. Typhimurium) causes a severe and lethal s...
While Salmonella enterica is seen as an archetypal facultative intracellular bacterial pathogen wher...
While Salmonella enterica is seen as an archetypal facultative intracellular bacterial pathogen wher...
© 2017 Dr. Newton Gil PeresBacterial infections that are chiefly caused by food or water contaminate...
Salmonella typhi is the causative organism for typhoid fever, a serious systemic disease in humans. ...
AbstractA novel adoptive transfer system was used to track the fate of naive Salmonella-specific CD4...
While CD4 Th1 cells are required for resistance to intramacrophage infections, adoptive transfer of ...
Invasive Salmonella infection is an important health problem that is worsening because of rising ant...
Invasive Salmonella infection is an important health problem that is worsening because of rising ant...
<div><p><em>Salmonella enterica</em> serovars are intracellular bacteria capable of causing typhoid ...
niversity of Minnesota Ph.D. dissertation. October 2010. Major: Microbiology, Immunology and Cancer ...
AbstractSuccessful immunity against Salmonella infections is dependent on the generation of CD4+ T h...
Salmonella enterica serovars are intracellular bacteria capable of causing typhoid fever and gastroe...
In this Pivotal Advance manuscript, the authors address the “paradox of Salmonella immunity and immu...
<div><p>Invasive <em>Salmonella</em> infection is an important health problem that is worsening beca...
Infection with Salmonella enterica serovar Typhimurium (S. Typhimurium) causes a severe and lethal s...