Objective: The objective of the present study was to determine the cellular level effect on glucose uptake and aldose reductase inhibitory activity of different extracts of traditional medicinal plant Psidium guajava.Methods: Psidium guajava was selected and subjected for successive extraction from non-polar to polar solvents and subjected to glucose uptake and aldose reductase inhibition assay.Results: Based on the results Psidium guajava methanolic extract (PGME) showed an enhancement in the glucose uptake and also up-regulates the gene and protein level expression of IRβ, IRS-1, PI3K and GLUT4. Wortmannin, a specific PI3K inhibitor confirms that the active PGME recruits glucose uptake through a PI3K dependent pathway. In the assay of al...
Background and Objective: Diabetes mellitus (DM) is the major health and economic problem through th...
Abundant natural products with medicinal properties have been used as food and traditional medicine ...
ABSTRACTGlucose is a key fuel in mammalian cells that import by a process of facilitative diffusion ...
BACKGROUND: The leaf and fruit of Psidium guajava L. are potential for neutraceutical beverage espec...
Background: Prevalence of diabetes mellitus is estimated to increase annually. Numerous people use t...
Doctor of Philosophy in Biochemistry. University of KwaZulu-Natal, Westville 2015.Diabetes mellitus ...
Objective: Diabetes mellitus is a chronic metabolic disease which affects our body's ability to use ...
Background: Psidium guajava L (Guava) belongs to the Myrtaceae family and has been claimed to posses...
Type 2 diabetes mellitus (T2DM) has become a major disease threatening human health worldwide. At pr...
Objective: To determine the anti-diabetic activity of combined aqueous extracts (1:1mixture) of dry ...
Abstract: Diabetes mellitus is one of the most common endocrine diseases and its type 2 is the major...
The leaves and fruits of Indonesian Syzygium spp such as white pakoba, red pakoba and bombongan have...
Objective: To evaluate the glucose uptake of (antidiabetic activity) crude pet-ethe,benzene,chlorofo...
Diabetes mellitus is a metabolic disease characterized by an increase in blood glucose levels or cal...
In Nigeria, rural inhabitants often resort to herbal remedies and dietary control for the treatment ...
Background and Objective: Diabetes mellitus (DM) is the major health and economic problem through th...
Abundant natural products with medicinal properties have been used as food and traditional medicine ...
ABSTRACTGlucose is a key fuel in mammalian cells that import by a process of facilitative diffusion ...
BACKGROUND: The leaf and fruit of Psidium guajava L. are potential for neutraceutical beverage espec...
Background: Prevalence of diabetes mellitus is estimated to increase annually. Numerous people use t...
Doctor of Philosophy in Biochemistry. University of KwaZulu-Natal, Westville 2015.Diabetes mellitus ...
Objective: Diabetes mellitus is a chronic metabolic disease which affects our body's ability to use ...
Background: Psidium guajava L (Guava) belongs to the Myrtaceae family and has been claimed to posses...
Type 2 diabetes mellitus (T2DM) has become a major disease threatening human health worldwide. At pr...
Objective: To determine the anti-diabetic activity of combined aqueous extracts (1:1mixture) of dry ...
Abstract: Diabetes mellitus is one of the most common endocrine diseases and its type 2 is the major...
The leaves and fruits of Indonesian Syzygium spp such as white pakoba, red pakoba and bombongan have...
Objective: To evaluate the glucose uptake of (antidiabetic activity) crude pet-ethe,benzene,chlorofo...
Diabetes mellitus is a metabolic disease characterized by an increase in blood glucose levels or cal...
In Nigeria, rural inhabitants often resort to herbal remedies and dietary control for the treatment ...
Background and Objective: Diabetes mellitus (DM) is the major health and economic problem through th...
Abundant natural products with medicinal properties have been used as food and traditional medicine ...
ABSTRACTGlucose is a key fuel in mammalian cells that import by a process of facilitative diffusion ...