EPIDEMIOLOGICAL STUDIES ON VARYING EXTENDED-SPECTRUM β-LACTAMASES PRODUCING UROPATHOGENIC BACTERIA

Objective: Urinary tract infection (UTI) is the most common serious infection during infancy, adult male and female, as well as at the time of pregnancy. UTI is also the most common nosocomial infection in many hospitals and accounts for approximately 35% of all hospital acquired infections. Hence the present study was aimed to screen the presence of multi-drug resistant bacterial pathogens among the urine samples collected from in and out patients of multi-speciality hospital. Methods: Standard microbiological laboratory protocols were followed and about 152 samples were processed and screened. Among them, 49 reported positive for the presence of urinary bacterial pathogens. Results: Among 49 isolates, Escherichia coli registered its prevalence in about 44 samples followed by Klebsiella spp. (4) and Pseudomones spp. (1). The gender wise distribution was found to be more among female patients (42%) than male patients (24%). The age wise distribution of infection among male and female patients was also noticed. Further, the multi-drug resistance of the isolates was done by using 8 antibiotics. Conclusion: All the isolates exhibited the multiple antibiotic resistance and the isolates showed 27 different antibiotic resistance patterns. This confirms the prevalence of ESBL producers among the urinary pathogens