Body Mass Index and Mortality in Blunt Trauma: The Right BMI can be Protective

Background: There are limited studies examining the role of BMI on mortality in the trauma population. The aim of this study was to analyze whether the obesity paradox exists in non-elderly patients with blunt trauma. Methods: A retrospective study was performed on the Trauma Quality Improvement Program (TQIP) database for 2016. All non-elderly patients aged 18-64, with blunt traumatic injuries were identified. A generalized additive model (GAM) was built to assess the association of mortality and BMI adjusted for age, gender, race, and injury severity score (ISS). Results: 28,475 patients (mean age = 42.5, SD = 14.3) were identified. 20,328 (71.4%) were male. Age (p \u3c 0.0001), gender (p \u3c 0.0001), and ISS (p \u3c 0.0001) had significant associations with mortality. After GAM, BMI showed a significant U-shaped association with mortality (EDF = 3.2, p = 0.003). A BMI range of 31.5 ± 0.9 kg/m2 was associated with the lowest mortality. Conclusion: High BMI can be a protective factor in mortality within non-elderly patients with blunt trauma. However, underweight or morbid obesity suggest a higher risk of mortality