Spectrum of Disease Manifestations in Patients with Selective Immunoglobulin E Deficiency
- César Picado
- Iñaki Ortiz de Landazuri
- Alexandru Vlagea
- Irina Bobolea
- Ebymar Arismendi
- Rosanel Amaro
- Jacobo Sellarés
- Joan Bartra
- Raimon Sanmarti
- José Hernandez-Rodriguez
- José-Manuel Mascaró
- Jordi Colmenero
- Eva C. Vaquero
- Mariona Pascal
DOIAbstract
Background: Selective IgE deficiency (SIgED) has been previously evaluated in selected patients from allergy units. This study investigates the effects of SIgED on the entire population in a hospital setting and sought to delineate in detail the clinical aspects of SIgED. Methods: A retrospective study of the data obtained from electronic medical records of 52 adult patients (56% female) with a mean age of 43 years and IgE levels of <2.0 kU/L with normal immunoglobulin (Ig) IgG, IgA, and IgM levels, seen at our hospital, without selection bias, from 2010 to 2019. Results: Recurrent upper respiratory infections were recorded in 18 (34.6%) patients, pneumonia was recorded in 16 (30.7%) patients, bronchiectasis was recorded in 16 (30.7%) patie...
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