Enantioselective synthesis of bronchodilating agent (R)-Salmeterol<sup> #</sup>

  • Ranganath, P L N
  • Anil, T
  • Narsaiah, A Venkat
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Publication date
October 2021
Publisher
NIScPR-CSIR, India

Abstract

1347-1352Synthesis of β2-adrenoreceptor agonist bronchodilator (R)-Salmeterol has been described with good yields. The synthesis commenced from commercially available starting materials, 4-hydroxy benzaldehyde and phenylbutanoic acid. The features of the synthetic strategy are Wittig olefination and Sharpless asymmetric dihydroxylation

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