Add to ORKGLung cancer is responsible for the highest cancer mortality worldwide. The prognosis for patients with advanced disease remains poor with five-year overall survival of <10%, highlighting the urgent unmet need for novel treatments. Oncolytic viruses (OV) are a promising form of IO that has demonstrated selective infection, replication and killing of tumour cells, as well as subsequent activation of anti-tumour immunity. Maraba virus, MG1, is one such OV that is currently being investigated in phase I/II clinical trials as part of a "prime-boost" cancer vaccine. This thesis explores the anti-cancer effects of clinical-grade Maraba virus (MG1) in a panel of lung cancer cell lines in vitro and then also in vivo in an immunocompetent murine lung...
Epithelial ovarian cancer is unique among most carcinomas in that metastasis occurs by direct dissem...
Copyright © 2013 Nicolas Boisgerault et al. This is an open access article distributed under the Cre...
Oncolytic viruses are replication competent, tumor selective and lyse cancer cells. Their potential ...
Despite recent advances in the targeted and immunological treatment of melanoma, the incidence of th...
International audienceOncolytic activity of the MG1 strain of the Maraba vesiculovirus has proven ef...
The use of oncolytic viruses (OVs) for cancer treatment is emerging as a successful strategy that co...
Similar to cancer cells, HIV-infected cells differ from HIV-uninfected cells in that they have alter...
Abstract Background Epithelial ovarian cancer exhibits extensive interpatient and intratumoral heter...
The rising demand for powerful oncolytic virotherapy agents has led to the identification of Maraba ...
Abstract Background Breast cancer is the most common ...
Oncolytic viruses (OVs) are effective anti-cancer agents, however their abilities to induce anti-tum...
The American Cancer Society estimates that in 2023, 1,958,310 new cancer cases and 609,820 cancer de...
Acute myeloid leukaemia (AML) is a cancer of the blood and bone marrow and is characterised by the o...
Oncolytic viruses are replication competent, tumor selective and lyse cancer cells. Their potential ...
Intrinsic and acquired drug resistance remains a fundamental obstacle to successful applications of ...
Epithelial ovarian cancer is unique among most carcinomas in that metastasis occurs by direct dissem...
Copyright © 2013 Nicolas Boisgerault et al. This is an open access article distributed under the Cre...
Oncolytic viruses are replication competent, tumor selective and lyse cancer cells. Their potential ...
Despite recent advances in the targeted and immunological treatment of melanoma, the incidence of th...
International audienceOncolytic activity of the MG1 strain of the Maraba vesiculovirus has proven ef...
The use of oncolytic viruses (OVs) for cancer treatment is emerging as a successful strategy that co...
Similar to cancer cells, HIV-infected cells differ from HIV-uninfected cells in that they have alter...
Abstract Background Epithelial ovarian cancer exhibits extensive interpatient and intratumoral heter...
The rising demand for powerful oncolytic virotherapy agents has led to the identification of Maraba ...
Abstract Background Breast cancer is the most common ...
Oncolytic viruses (OVs) are effective anti-cancer agents, however their abilities to induce anti-tum...
The American Cancer Society estimates that in 2023, 1,958,310 new cancer cases and 609,820 cancer de...
Acute myeloid leukaemia (AML) is a cancer of the blood and bone marrow and is characterised by the o...
Oncolytic viruses are replication competent, tumor selective and lyse cancer cells. Their potential ...
Intrinsic and acquired drug resistance remains a fundamental obstacle to successful applications of ...
Epithelial ovarian cancer is unique among most carcinomas in that metastasis occurs by direct dissem...
Copyright © 2013 Nicolas Boisgerault et al. This is an open access article distributed under the Cre...
Oncolytic viruses are replication competent, tumor selective and lyse cancer cells. Their potential ...