The Synthesis of Some Disubstituted Derivatives of p,p\u27-bis- (Pyrimidyl-2-sulphamyl)-carbanilide. II

In an earlier paper1 we\u27 describ ed the preparation of some disub stituted derivatives of p,p\u27-bis-(sulphamyl)-carbanilide by the condensation of carbanilide- p,p\u27-disulphbnic acid dichloride with various heterocyclic amines, and their hydrolysis to the corresponding sulphonamides. This paper reports our work <:oncerned with the synthesis of p,p\u27-bis-(pyrimidyl-2-sulphamyl)-carbanilides by condensation of p,p\u27-bis-(N-guanylsulphamyl)-carbanUide with various appropriate s ub stituted aliphatic carbonyl compounds. The preparation was performed according to the standard procedures for the synthesis of substituted .sulphapyrimidines2- 4 and pyrimidines