Activity of serum transaminase in occupational exposure to trichlorethylene

Ispitana je aktivnost serumske transaminaze u grupi od 20 radnika profesionalno eksponiranih trikloretilenu. Aktivnost transaminaze određivana je ujutro prije početka rada i na kraju smjene. Kod većeg dijela radnika SGPT bio je lagano povišen, a vrijednosti SGPT na kraju radne smjene statistički su značajno veće od vrijednost! na početku rada. Prihvati li se tumačenje da je utvrđeno povišenje aktivnosti SGPT izraz početnih lezija jetrenih stanica, mogao bi se izvesti zaključak da tehnički trikloretilen ima potencijalno lagani hepatotoksički učinak.The activity of serum transaminase in a group of 20 workers with occupational exposure to trichlorethylene was examined. The activity of transaminase was determined in the morning, before work, and at the end of the shift. In the majority of workers SGPT values were slightly increased. At the end of work the SGPT values were significantly higher than at the beginning of work. If the assumption that the evidenced increase of the activity of SGPT indicates the initial lesions of liver cells is accepted, it may be concluded from the results obtained in this study that technical trichlorethylene has a slight hepatotoxic effect