Pathological vasospasm and free radical production contribute to skin flap survival. This study was undertaken to determine if combination therapy with anti-free radical agent-allopurinol and the vasodilatoprostaglandin E₁results in the synergistic enhacement of skin flap survival in rats. Twenty Sprague-Dawley rats were divided into four groups. With five rats in each group, group I being the control, group II was given intravenous allopurinol, group III was given transdermal PGE₁, and group IV was given both intravenous allopurinol and transdermal PGE₁. Control group demonstrated 27.7±3.0% skin flap survival. Compared to the control group, the increase in survival rate in PGE₁ group was statistically significant with a p value of less tha...
BACKGROUND: Microcirculation dysfunction, as a consequence of localized vascular insufficiency, is c...
There are plenty of recent studies showing the influence of different drugs on the survival of the c...
AbstractBackground: Skin flaps are among the basic treatment options in the reconstruction of soft t...
Prostaglandin E₁(PGE₁) is known to have various physiological action such as vasodilatation, decreas...
Background: Secondary venous ischemia caused by anastomotic failure is one of the major reasons for ...
The aim of this study is to examine and compare the effects of topical prostacyclin and prostaglandi...
Background: Random pattern flap is a common reconstructive surgery procedure but its necrosis is a c...
Polydeoxyribonucleotide (PDRN) has multiple vascular actions such as angiogenesis and production of ...
Dept. of Medicine/석사Polydeoxyribonuceotide (PDRN) has multiple vascular actions such as angiogenesis...
Abstract Beneficial effects could be achieved by various agents such as nitroglycerin, botulinum tox...
Objective: Phosphodiesterase-5 inhibitors, used to increase penile blood flow in erec-tile dysfuncti...
Cyclooxygenase-2(COX-2) inhibitors provide desired analgesic effects after injury or surgery, but ev...
BACKGROUND: Cyclooxygenase-2(COX-2) inhibitors provide desired analgesic effects after injury or sur...
The effect of pentoxifylline as a hemorrheologic agent on skin flap survival has been observed. A ca...
AbstractManagement of skin avulsion with tissue exposure is a challenge for plastic surgeons. Clinic...
BACKGROUND: Microcirculation dysfunction, as a consequence of localized vascular insufficiency, is c...
There are plenty of recent studies showing the influence of different drugs on the survival of the c...
AbstractBackground: Skin flaps are among the basic treatment options in the reconstruction of soft t...
Prostaglandin E₁(PGE₁) is known to have various physiological action such as vasodilatation, decreas...
Background: Secondary venous ischemia caused by anastomotic failure is one of the major reasons for ...
The aim of this study is to examine and compare the effects of topical prostacyclin and prostaglandi...
Background: Random pattern flap is a common reconstructive surgery procedure but its necrosis is a c...
Polydeoxyribonucleotide (PDRN) has multiple vascular actions such as angiogenesis and production of ...
Dept. of Medicine/석사Polydeoxyribonuceotide (PDRN) has multiple vascular actions such as angiogenesis...
Abstract Beneficial effects could be achieved by various agents such as nitroglycerin, botulinum tox...
Objective: Phosphodiesterase-5 inhibitors, used to increase penile blood flow in erec-tile dysfuncti...
Cyclooxygenase-2(COX-2) inhibitors provide desired analgesic effects after injury or surgery, but ev...
BACKGROUND: Cyclooxygenase-2(COX-2) inhibitors provide desired analgesic effects after injury or sur...
The effect of pentoxifylline as a hemorrheologic agent on skin flap survival has been observed. A ca...
AbstractManagement of skin avulsion with tissue exposure is a challenge for plastic surgeons. Clinic...
BACKGROUND: Microcirculation dysfunction, as a consequence of localized vascular insufficiency, is c...
There are plenty of recent studies showing the influence of different drugs on the survival of the c...
AbstractBackground: Skin flaps are among the basic treatment options in the reconstruction of soft t...