Glutathione peroxidase 1 (Gpx1) and peroxiredoxin 2 (Prdx2) belong to the thiol peroxidase family of antioxidants, and have been studied for their antioxidant functions and roles in cancers. However, the physiological significance of Gpx1 and Prdx2 during vertebrate embryogenesis are lacking. Currently, we investigated the functional roles of Gpx1 and Prdx2 during vertebrate embryogenesis using Xenopus laevis as a vertebrate model. Our investigations revealed the zygotic nature of gpx1 having its localization in the eye region of developing embryos, whereas prdx2 exhibited a maternal nature and were localized in embryonic ventral blood islands. Furthermore, the gpx1-morphants exhibited malformed eyes with incompletely detached lenses. Howev...
Accumulated evidence indicates that maternal alcohol consumption causes fetal enteric damage and gro...
Spatial and temporal expression and regulation of the antioxidant enzymes, glutathione peroxidase(GS...
Due, in part, to its elevated metabolism, the central nervous system (CNS) is exposed to considerabl...
Glutathione peroxidase 1 (Gpx1) and peroxiredoxin 2 (Prdx2) belong to the thiol peroxidase family of...
Glutathione peroxidase 3 (GPx3) belongs to the glutathione peroxidase family of selenoproteins and i...
Development in the frog, Xenopus laevis, requires the utilization of yolk glyco- lipo-proteins in a ...
Aims: Peroxiredoxin5 (Prdx5) - a thioredoxin peroxidase is an antioxidant enzyme that is widely stud...
Peroxiredoxin1 (Prdx1) is an antioxidant enzyme belonging to the peroxiredoxin family of proteins. P...
PURPOSE. To study the molecular mechanisms underlying alcohol-induced ocular anomalies in Xenopus em...
AbstractThe RING finger ubiquitin ligase seven in absentia homolog 2 (Siah2) was identified in the R...
BACKGROUND: Peroxisomes are organelles whose roles in fatty acid metabolism and reactive oxygen spec...
The cellular redox state is a central regulator of embryonic development. Redox homeostasis and thi...
Reactive oxygen species (ROS) are formed and degraded in all aerobic organisms, but their role durin...
Peroxisomes are organelles whose roles in fatty acid metabolism and reactive oxygen species (ROS) el...
Glutaredoxin belongs to the oxidoreductase family with cytosolic glutaredoxin 1 (Grx1) and mitochond...
Accumulated evidence indicates that maternal alcohol consumption causes fetal enteric damage and gro...
Spatial and temporal expression and regulation of the antioxidant enzymes, glutathione peroxidase(GS...
Due, in part, to its elevated metabolism, the central nervous system (CNS) is exposed to considerabl...
Glutathione peroxidase 1 (Gpx1) and peroxiredoxin 2 (Prdx2) belong to the thiol peroxidase family of...
Glutathione peroxidase 3 (GPx3) belongs to the glutathione peroxidase family of selenoproteins and i...
Development in the frog, Xenopus laevis, requires the utilization of yolk glyco- lipo-proteins in a ...
Aims: Peroxiredoxin5 (Prdx5) - a thioredoxin peroxidase is an antioxidant enzyme that is widely stud...
Peroxiredoxin1 (Prdx1) is an antioxidant enzyme belonging to the peroxiredoxin family of proteins. P...
PURPOSE. To study the molecular mechanisms underlying alcohol-induced ocular anomalies in Xenopus em...
AbstractThe RING finger ubiquitin ligase seven in absentia homolog 2 (Siah2) was identified in the R...
BACKGROUND: Peroxisomes are organelles whose roles in fatty acid metabolism and reactive oxygen spec...
The cellular redox state is a central regulator of embryonic development. Redox homeostasis and thi...
Reactive oxygen species (ROS) are formed and degraded in all aerobic organisms, but their role durin...
Peroxisomes are organelles whose roles in fatty acid metabolism and reactive oxygen species (ROS) el...
Glutaredoxin belongs to the oxidoreductase family with cytosolic glutaredoxin 1 (Grx1) and mitochond...
Accumulated evidence indicates that maternal alcohol consumption causes fetal enteric damage and gro...
Spatial and temporal expression and regulation of the antioxidant enzymes, glutathione peroxidase(GS...
Due, in part, to its elevated metabolism, the central nervous system (CNS) is exposed to considerabl...