The impact of the Mediterranean diet on glycemic regulation in obese patients with insulin resistance

Pretilost je zajedno s pridruženim komplikacijama velik izazov za zdravstveni sustav danas s obzirom na to da broj pretilih osoba bilježi stalan porast. Kao jedna od najčešćih komplikacija pretilosti navodi se šećerna bolest tipa 2, a kojoj prethodi stanje inzulinske rezistencije, čijim pravovremenim zbrinjavanjem je moguće odgoditi razvoj šećerne bolesti. Kao neupitno djelotvorna u odgodi nastanka šećerne bolesti i zbrinjavanju inzulinske rezistencije pokazala se prehrana, a kao posebno povoljna ona mediteranskog karaktera. Cilj ovog rada bio je ispitati utjecaj mediteransko – redukcijske dijete na različite antropometrijske i biokemijske parametre kod pacijenata s inzulinskom rezistencijom. Svi su pacijenti do kraja trajanja praćenja reducirali svoju tjelesnu masu te značajno snizili koncentraciju glukoze u krvi, a pozitivan učinak vidljiv je i na parametre poput koncentracije ukupnog kolesterola, LDL–a, HDL–a i triglicerida.Along with its associated complications, obesity represents a major challenge for health care system since the number of people with obesity is on the rise nowadays. One of the most common complications of obesity is type 2 diabetes, which is preceded by a state of insulin resistance which, if not treated, can lead to development of diabetes. The diet therapy proved to be unquestionably effective in delaying the onset and management of insulin resistance especially diet with Mediterranean characteristics. The aim of this thesis was to examine the effect of Mediterranean – reduction diet on various anthropometric and biochemical parameters in hospital patients with insulin resistance. By the end of the monitoring, all patients reduced their body weight and significantly lowered their blood glucose concentrations. Positive effect was also seen on parameters such as total cholesterol, LDL, HDL and triglycerides concentrations