Copper (Cu) plays a pivotal role in cancer progression by acting as a co-factor that regulates the activity of many enzymes and structural proteins in cancer cells. Therefore, Cu-based complexes have been investigated as novel anticancer metallodrugs and are considered as a complementary strategy for currently used platinum agents with undesirable general toxicity. Due to the high failure rate and increased cost of new drugs, there is a global drive towards the repositioning of known drugs for cancer treatment in recent years. Disulfiram (DSF) is a first-line antialcoholism drug used in clinics for more than 65 yr. In combination with Cu, it has shown great potential as an anticancer drug by targeting a wide range of cancers. The reaction b...
Copper is an essential trace element for living organisms and, in particular, is the third most abu...
Background: Disulfiram (DS), an anti-alcoholism drug, demonstrates strong antitumor activity in a co...
Background: Disulfiram (DSF) is a well-tolerated, inexpensive, generic drug that has been in use to ...
�� 2021 The Authors. Published by Frontiers Media. This is an open access article available under a ...
�� 2018 The Author(s). Background: Disulfiram (DS), an antialcoholism medicine, demonstrated strong ...
The anticancer activity of disulfiram (DS) is copper(II) (Cu)-depen-dent. This study investigated th...
The anticancer activity of disulfiram (DS) is copper(II) (Cu)-depen-dent. This study investigated th...
BACKGROUND:Disulfiram (DSF), which is used to treat alcohol dependence, has been reported to have an...
Although approved as an alcohol-abuse drug, disulfiram (DSF) exhibited potential anticancer activity...
Abstract Background Disulfiram (DS), an antialcoholism medicine, demonstrated strong anticancer acti...
Disulfiram (DSF) is an aldehyde dehydrogenase inhibitor currently used for the treatment of alcoholi...
A thesis submitted in partial fulfilment of the requirement of the University of Wolverhampton for t...
Differentiated thyroid carcinomas (DTCs), which have papillary and follicular types, are common endo...
Disulfiram (DSF), an alcohol-aversion drug, has been explored for cancer treatment. Copper diethyldi...
Copper is an essential trace element for living organisms and, in particular, is the third most abun...
Copper is an essential trace element for living organisms and, in particular, is the third most abu...
Background: Disulfiram (DS), an anti-alcoholism drug, demonstrates strong antitumor activity in a co...
Background: Disulfiram (DSF) is a well-tolerated, inexpensive, generic drug that has been in use to ...
�� 2021 The Authors. Published by Frontiers Media. This is an open access article available under a ...
�� 2018 The Author(s). Background: Disulfiram (DS), an antialcoholism medicine, demonstrated strong ...
The anticancer activity of disulfiram (DS) is copper(II) (Cu)-depen-dent. This study investigated th...
The anticancer activity of disulfiram (DS) is copper(II) (Cu)-depen-dent. This study investigated th...
BACKGROUND:Disulfiram (DSF), which is used to treat alcohol dependence, has been reported to have an...
Although approved as an alcohol-abuse drug, disulfiram (DSF) exhibited potential anticancer activity...
Abstract Background Disulfiram (DS), an antialcoholism medicine, demonstrated strong anticancer acti...
Disulfiram (DSF) is an aldehyde dehydrogenase inhibitor currently used for the treatment of alcoholi...
A thesis submitted in partial fulfilment of the requirement of the University of Wolverhampton for t...
Differentiated thyroid carcinomas (DTCs), which have papillary and follicular types, are common endo...
Disulfiram (DSF), an alcohol-aversion drug, has been explored for cancer treatment. Copper diethyldi...
Copper is an essential trace element for living organisms and, in particular, is the third most abun...
Copper is an essential trace element for living organisms and, in particular, is the third most abu...
Background: Disulfiram (DS), an anti-alcoholism drug, demonstrates strong antitumor activity in a co...
Background: Disulfiram (DSF) is a well-tolerated, inexpensive, generic drug that has been in use to ...