Tumor of the Nose – A Rare Manifestation of a Metastatic Lung Cancer

Aleksandra Bolewska,1 Monika Słowińska,1 Agata Błońska,1 Justyna Ceryn,2 Bartłomiej Grala,3 Joanna Narbutt,2 Magdalena Ciążyńska,4 Wojciech Małecki,5 Małgorzata Skibińska,2 Aleksandra Lesiak,2 Elwira Paluchowska,1 Witold Owczarek1 1Department of Dermatology, Military Institute of Medicine, Warsaw, Poland; 2Department of Dermatology, Pediatric Dermatology and Oncology, Medical University of Lodz, Łódź, Poland; 3Department of Pathology, Military Institute of Medicine, Warsaw, Poland; 4Department of Proliferative Diseases, Nicolaus Copernicus Multidisciplinary Centre for Oncology and Traumatology, Łódź, Poland; 5Department of Clinical Oncology and Chemotherapy, Poddębice Health Centre, Poddębice, PolandCorrespondence: Aleksandra Bolewska Tel +48 261 816 241; +48 604 783 340Email aleksandra.bolewska@wp.plAbstract: Lung cancer most often metastasizes to the central nervous system, bone and liver. Although metastases to the skin are quite rare, it is estimated that they may be the first clinical manifestation of this disease in 0.7%– 12% of cases. Metastases to the skin are caused by adenocarcinoma (about 30%), squamous cell carcinoma (30%) and undifferentiated carcinoma (40%). Nasal tip metastases are extremely rare. They can be confused with more common skin problems, including non-melanoma skin cancers, rhinophyma, inflammatory tumors or infectious diseases. We report two patients with a tumor on the nose, which proved to be the first sign of the metastatic lung cancer.Keywords: lung cancer, skin metastasis, ulceration, tumo