International audienceFrancisella tularensis is the causative agent of tularemia. Because of its extreme infectivity and high mortality rate, this pathogen was classified as a biothreat agent. Francisella spp are strict aerobe and ubiquinone (UQ) has been previously identified in these bacteria. While the UQ biosynthetic pathways were extensively studied in Escherichia coli allowing the identification of fifteen Ubi-proteins to date, little is known about Francisella spp. In this study, and using Francisella novicida as a surrogate organism, we first identified UQ 8 as the major quinone found in the membranes of this bacterium. Then, we characterized the UQ biosynthetic pathway in F. novicida using a combination of bioinformatics, genetics ...
Francisella tularensis is the causative agent in tularemia for which the high prevalence of treatmen...
<div><p>The transcription factors MglA and SspA of <em>Francisella tularensis</em> form a heterodime...
An emerging paradigm shift in bacterial pathogenesis has resulted in renewed interest in metabolism ...
International audienceFrancisella tularensis is the causative agent of tularemia. Because of its ext...
Thesis (Ph.D.)--University of Washington, 2020The survival of pathogenic intracellular bacteria reli...
International audienceFrancisella tularensis is the causative agent in tularemia for which the high ...
Francisella tularensis, the causative agent of tularemia, lacks typical bacterial virulence factors ...
The potential bioterror agent Francisella tularensis subspecies tularensis (F. tularensis) is an int...
Francisella tularensis is a Gram-negative bacterium responsible for causing tularemia in the norther...
The transcription factors MglA and SspA of Francisella tularensis form a heterodimer complex and int...
Francisella tularensis is a Gram-negative bacterium responsible for causing tularemia in the norther...
2014 Fall.Francisella tularensis is an extremely infectious intracellular bacterium and the etiologi...
The transcription factors MglA and SspA of Francisella tularensis form a heterodimer complex and int...
Advisor: Meganathan, Rangaswamy.Committee members: Bujarski, Jozef; Hagen, Timothy J.; Yin, Yanbin; ...
Francisella tularensis is the causative agent in tularemia for which the high prevalence of treatmen...
<div><p>The transcription factors MglA and SspA of <em>Francisella tularensis</em> form a heterodime...
An emerging paradigm shift in bacterial pathogenesis has resulted in renewed interest in metabolism ...
International audienceFrancisella tularensis is the causative agent of tularemia. Because of its ext...
Thesis (Ph.D.)--University of Washington, 2020The survival of pathogenic intracellular bacteria reli...
International audienceFrancisella tularensis is the causative agent in tularemia for which the high ...
Francisella tularensis, the causative agent of tularemia, lacks typical bacterial virulence factors ...
The potential bioterror agent Francisella tularensis subspecies tularensis (F. tularensis) is an int...
Francisella tularensis is a Gram-negative bacterium responsible for causing tularemia in the norther...
The transcription factors MglA and SspA of Francisella tularensis form a heterodimer complex and int...
Francisella tularensis is a Gram-negative bacterium responsible for causing tularemia in the norther...
2014 Fall.Francisella tularensis is an extremely infectious intracellular bacterium and the etiologi...
The transcription factors MglA and SspA of Francisella tularensis form a heterodimer complex and int...
Advisor: Meganathan, Rangaswamy.Committee members: Bujarski, Jozef; Hagen, Timothy J.; Yin, Yanbin; ...
Francisella tularensis is the causative agent in tularemia for which the high prevalence of treatmen...
<div><p>The transcription factors MglA and SspA of <em>Francisella tularensis</em> form a heterodime...
An emerging paradigm shift in bacterial pathogenesis has resulted in renewed interest in metabolism ...