International audienceVoltage-gated sodium channels (VGSCs) are considered to be one of the most important ion channels given their remarkable physiological role. VGSCs constitute a family of large transmembrane proteins that allow transmission, generation, and propagation of action potentials. This occurs by conducting Na+ ions through the membrane, supporting cell excitability and communication signals in various systems. As a result, a wide range of coordination and physiological functions, from locomotion to cognition, can be accomplished. Drugs that target and alter the molecular mechanism of VGSCs’ function have highly contributed to the discovery and perception of the function and the structure of this channel. Among those drugs are ...
Human intoxication with the seafood poison ciguatoxin, a dinoflagellate polyether that activates vol...
Voltage-gated sodium channels (VGSCs) are important membrane protein carrying on the molecular basis...
hNav1.7 is a voltage-gated sodium human channel associated with neuropathic pain. Saxitoxin (STX), a...
International audienceVoltage-gated sodium channels (VGSCs) are considered to be one of the most imp...
International audienceVoltage-gated sodium channels (Nav) are key components for nerve excitability....
Voltage-gated sodium channels (VGSCs) play a central role in the generation and propagation of actio...
Abstract: Eukaryotic, voltage-gated sodium (NaV) channels are large membrane proteins which underlie...
Voltage gated sodium channels (VGSC) are membrane proteins that serve an important function in the c...
Voltage-gated Sodium Channels (VGSCs) are large transmembrane proteins that conduct sodium ions acro...
Many human cardiovascular and neurological disorders (such as ischemia, epileptic seizures, traumati...
During their evolution, animals have developed a set of cysteine-rich peptides capable of binding va...
International audienceParalytic shellfish toxins (PST) bind to voltage-gated sodium channels (Nav) a...
The rising phase of the action potential in excitable cells is mediated by voltage-gated sodium chan...
AbstractDuring their evolution, animals have developed a set of cysteine-rich peptides capable of bi...
Human intoxication with the seafood poison ciguatoxin, a dinoflagellate polyether that activates vol...
Voltage-gated sodium channels (VGSCs) are important membrane protein carrying on the molecular basis...
hNav1.7 is a voltage-gated sodium human channel associated with neuropathic pain. Saxitoxin (STX), a...
International audienceVoltage-gated sodium channels (VGSCs) are considered to be one of the most imp...
International audienceVoltage-gated sodium channels (Nav) are key components for nerve excitability....
Voltage-gated sodium channels (VGSCs) play a central role in the generation and propagation of actio...
Abstract: Eukaryotic, voltage-gated sodium (NaV) channels are large membrane proteins which underlie...
Voltage gated sodium channels (VGSC) are membrane proteins that serve an important function in the c...
Voltage-gated Sodium Channels (VGSCs) are large transmembrane proteins that conduct sodium ions acro...
Many human cardiovascular and neurological disorders (such as ischemia, epileptic seizures, traumati...
During their evolution, animals have developed a set of cysteine-rich peptides capable of binding va...
International audienceParalytic shellfish toxins (PST) bind to voltage-gated sodium channels (Nav) a...
The rising phase of the action potential in excitable cells is mediated by voltage-gated sodium chan...
AbstractDuring their evolution, animals have developed a set of cysteine-rich peptides capable of bi...
Human intoxication with the seafood poison ciguatoxin, a dinoflagellate polyether that activates vol...
Voltage-gated sodium channels (VGSCs) are important membrane protein carrying on the molecular basis...
hNav1.7 is a voltage-gated sodium human channel associated with neuropathic pain. Saxitoxin (STX), a...