Therapeutic cancer vaccines have undergone a resurgence in the past decade. A better understanding of the breadth of tumour-associated antigens, the native immune response and development of novel technologies for antigen delivery has facilitated improved vaccine design. The goal of therapeutic cancer vaccines is to induce tumour regression, eradicate minimal residual disease, establish lasting antitumour memory and avoid non-specific or adverse reactions. However, tumour-induced immunosuppression and immunoresistance pose significant challenges to achieving this goal. In this Review, we deliberate on how to improve and expand the antigen repertoire for vaccines, consider developments in vaccine platforms and explore antigen-agnostic in sit...
Immuno-oncology (IO) has revolutionized the treatment of cancer by harnessing and boosting the inher...
Concerted efforts of tumor immunologists over more than two decades contributed numerous well-define...
A remarkable advance in tumor immunology during the last decade is the elucidation of the antigenic ...
Therapeutic cancer vaccines have become increasingly qualified for use in personalized cancer immuno...
Therapeutic cancer vaccines have become increasingly qualified for use in personalized cancer immuno...
Cancer vaccines represent a promising therapeutic approach for which prime time is imminent. However...
International audienceConsidering the high importance of immune surveillance and immune escape in th...
Tumor vaccines able to deliver specific antigen to the immune system are now available and are begin...
Abstract Immunotherapy is an alternative to more traditional forms of anticancer therapy that has th...
Treating cancer with vaccines has been a challenging field of investigation since the 1950s. Over th...
The therapeutic potential of host-specific and tumour-specific immune responses is well recognized a...
Multimodal approaches are nowadays successfully applied in cancer therapy. Primary locally acting th...
Abstract Immunotherapy has become a standard approach for cancer management, through the use of cyto...
Attempts to create vaccines for humans against invading pathogens such as viruses and bacteria have ...
IntroductionBreakthroughs in cancer immunotherapy have spurred interest in the development of vaccin...
Immuno-oncology (IO) has revolutionized the treatment of cancer by harnessing and boosting the inher...
Concerted efforts of tumor immunologists over more than two decades contributed numerous well-define...
A remarkable advance in tumor immunology during the last decade is the elucidation of the antigenic ...
Therapeutic cancer vaccines have become increasingly qualified for use in personalized cancer immuno...
Therapeutic cancer vaccines have become increasingly qualified for use in personalized cancer immuno...
Cancer vaccines represent a promising therapeutic approach for which prime time is imminent. However...
International audienceConsidering the high importance of immune surveillance and immune escape in th...
Tumor vaccines able to deliver specific antigen to the immune system are now available and are begin...
Abstract Immunotherapy is an alternative to more traditional forms of anticancer therapy that has th...
Treating cancer with vaccines has been a challenging field of investigation since the 1950s. Over th...
The therapeutic potential of host-specific and tumour-specific immune responses is well recognized a...
Multimodal approaches are nowadays successfully applied in cancer therapy. Primary locally acting th...
Abstract Immunotherapy has become a standard approach for cancer management, through the use of cyto...
Attempts to create vaccines for humans against invading pathogens such as viruses and bacteria have ...
IntroductionBreakthroughs in cancer immunotherapy have spurred interest in the development of vaccin...
Immuno-oncology (IO) has revolutionized the treatment of cancer by harnessing and boosting the inher...
Concerted efforts of tumor immunologists over more than two decades contributed numerous well-define...
A remarkable advance in tumor immunology during the last decade is the elucidation of the antigenic ...