Different species exposed to a common stress may adapt by mutations in shared pathways or in unique systems, depending on how past environments have molded their genomes. Understanding how diverse bacterial pathogens evolve in response to an antimicrobial treatment is a pressing example of this problem, where discovery of molecular parallelism could lead to clinically useful predictions. Evolution experiments with pathogens in environments containing antibiotics, combined with periodic whole-population genome sequencing, can be used to identify many contending routes to antimicrobial resistance. We separately propagated two clinically relevant Gram-negative pathogens, Pseudomonas aeruginosa and Acinetobacter baumannii, in increasing concent...
Antibiotic resistance is a major threat to public health. Understanding how it evolves,\ud and the g...
The use of bacteriophages against pathogenic bacteria in health care and in the food industry is now...
Understanding how evolution of antimicrobial resistance increases resistance to other drugs is a cha...
Different species exposed to a common stress may adapt by mutations in shared pathways or in unique ...
ABSTRACT Different species exposed to a common stress may adapt by mutations in shared pathways or i...
Microbial evolution has critical implications for human health, from the increasing prevalence of an...
The present work examines the evolutionary trajectories of replicate Pseudomonas aeruginosa cultures...
Bacteria in biofilms have higher antibiotic tolerance than their planktonic counterparts. A major ou...
Adaptation is likely to be an important determinant of the success of many pathogens, for example wh...
Adaptation is likely to be an important determinant of the success of many pathogens, for example wh...
Pseudomonas aeruginosa, a major cause of nosocomial and chronic infections, is considered a paradigm...
Bacterial persistence represents a simple of phenotypic heterogeneity, whereby a proportion of cells...
<div><p>Adaptation is likely to be an important determinant of the success of many pathogens, for ex...
Different works have explored independently the evolution toward antibiotic resistance and the role ...
The continuing emergence and spread of antibiotic resistant bacteria are a threat to various applica...
Antibiotic resistance is a major threat to public health. Understanding how it evolves,\ud and the g...
The use of bacteriophages against pathogenic bacteria in health care and in the food industry is now...
Understanding how evolution of antimicrobial resistance increases resistance to other drugs is a cha...
Different species exposed to a common stress may adapt by mutations in shared pathways or in unique ...
ABSTRACT Different species exposed to a common stress may adapt by mutations in shared pathways or i...
Microbial evolution has critical implications for human health, from the increasing prevalence of an...
The present work examines the evolutionary trajectories of replicate Pseudomonas aeruginosa cultures...
Bacteria in biofilms have higher antibiotic tolerance than their planktonic counterparts. A major ou...
Adaptation is likely to be an important determinant of the success of many pathogens, for example wh...
Adaptation is likely to be an important determinant of the success of many pathogens, for example wh...
Pseudomonas aeruginosa, a major cause of nosocomial and chronic infections, is considered a paradigm...
Bacterial persistence represents a simple of phenotypic heterogeneity, whereby a proportion of cells...
<div><p>Adaptation is likely to be an important determinant of the success of many pathogens, for ex...
Different works have explored independently the evolution toward antibiotic resistance and the role ...
The continuing emergence and spread of antibiotic resistant bacteria are a threat to various applica...
Antibiotic resistance is a major threat to public health. Understanding how it evolves,\ud and the g...
The use of bacteriophages against pathogenic bacteria in health care and in the food industry is now...
Understanding how evolution of antimicrobial resistance increases resistance to other drugs is a cha...