Propolins and glyasperin a from stingless bee nests

Chemical investigation of the dichloromethane extracts of the propolis collected from bee (Tetragonulabiroi Friese) hives in San Roque, Sorsogon, Philippines afforded propolin A (1), propolin E (2), propolinH (3), glyasperin A (4), squalene, a mixture of lupeol, α-amyrin and β-amyrin, and another mixtureof urs-12-en-3-one, olean-12-en-3-one and lup-12-en-3-one. The structures of 2–4 were elucidated byextensive 1D and 2D (COSY, HSQC, and HMBC) NMR spectroscopy, while 1 was identified by comparisonof its NMR data with 2. © 2015 2015 Sociedade Brasileira de Farmacognosia. Published by Elsevier Editora Ltda. All rights reserved