D-Aspartic Acid As a Nutritional Aid To Increase Serum Testosterone

The purpose of this proposed study was to determine the potential changes in testosterone (free and total) and estradiol over a four-week intervention period using D-aspartic acid (DAA) in men. Twenty-four physically active men, aged 18-39 years, were randomly assigned to two groups (conditions) using a placebo-controlled, double-blind design. Baseline values for all hormones were compared to values measured at the end of two and four weeks of DAA administration, provided at a dosage of 3.12g, compared to the placebo. Data were analyzed using a 2 (condition) x 3 (time) analysis of variance. No interaction or main effects were noted for any hormonal variable (p\u3e0.05), with similar values noted between groups and across time. In conclusion, DAA supplementation for a 28 day period does not increase serum total or free testosterone in young, healthy men. Moreover, DAA has no impact on serum estradiol concentrations. Future studies may be designed to investigate the impact of DAA on testosterone and associated health parameters in a sample of older men and/or those with low testosterone concentrations