Study of Incidence of Carcinoma Prostate in Central India With Reference To Gleason’s grading

Introduction: Prostate cancer is the most common non dermatologic cancer and the second most common cause of cancer related death in men. Although most prostate cancers are relatively slow growing and remain clinically unrecognized, their course is often unpredictable in terms of its speed of progression, perhaps because of the considerable heterogeneity of the histologic grade and a multitude of other factors that affect tumor growth. Material and method: The present study was carried out in the Department of Pathology, L.N. Medical College, Bhopa, India. It was both a prospective and a retrospective study of 310 prostatic biopsies /TUR (Trans-urethral resection) prostate chips. Result: Among 310 Prostate biopsies, 276 cases (89%) were of benign prostatic hyperplasia, 8 cases (2.5%) were of benign prostatic hyperplasia with prostatic intraepithelial neoplasia and 26 cases (8.38%) were of adenocarcinoma prostate. Discussion: Higher incidence of adenocarcinoma prostate could be due to the fact that in the absence of proper screening programme in our country, majority of the tumours are diagnosed incidentally when patients present with obstructive symptoms