Interleukin-28 gene polymorphisms may contribute to HBsAg persistence and the development of HBeAg-negative chronic hepatitis B
- Karatayli, Senem C.
- Bozdayi, Mithat
- Karatayli, Ersin
- Ozturk, Tugba
- Husseini, Abbas A.
- Albayrak, Rabia
- Ozkan, Muhip
- Kalaylioglu, Zeynep
- YALÇIN, KENDAL
- Cinar, Kubilay
- İDİLMAN, RAMAZAN
- Yurdaydin, Cihan
DOIAbstract
Background & AimsAim of this study was to investigate whether a potential association exists between several single nucleotide polymorphisms (SNPs) of the IL-28B gene (rs12979860, rs1188122, rs8099917, rs8105790, rs12980275) and HBsAg persistence. Further, a potential effect on the development of HBeAg-negative CHB vs. inactive HBsAg carrier state was assessed in a genotype D HBV cohort. A cohort of chronic HDV patients was also used to see if they behave differently compared to chronic HBV patients
Add to ORKG