CYP1A is known to play important roles in the metabolism, detoxification and bioactivation of carcinogens and other xenobiotics in animals including fish. In our laboratory, CYP1A1 was obtained in a highly purified form with a specific content of 15-17 nmol P450 per mg protein from liver microsomes of feral fish, leaping mullet (Liza saliens). Purified mullet CYP1A1 showed a very high substrate specificities for 7-ethoxyresorufin and 7-methoxyresorufin in a reconstituted system containing purified fish P450 reductase and lipid. In addition, effects of each individual components of the reconstituted system, i.e., CYP1A1 and P450 reductase on 7-methoxyresorufin O-demethylase (MROD) activity were studied. 7-ethoxyresorufin O-deethylase (EROD) ...
Content of cytochromes b(5) and P-450, and activities of NADPH-cytochrome c (P-450) reductase (NCR) ...
Hepatic monooxy genase activities were studied in microsomal fractions from two species of freshwate...
In this study, feral leaping mullet (Liza saliens) liver cytosolic glutathione S-transferases (GSTs)...
CYP1A is known to play important roles in the metabolism, detoxification and bioactivation of carcin...
CYP1A is known to play important roles in the metabolism, detoxification and bioactivation of carcin...
NADPH-cytochrome P450 reductase was purified to electrophoretic homogeneity from detergent-solubiliz...
In this study, CYP2B-immunoreactive protein was purified to electrophoretic homogeneity from the liv...
In this study, we examined whether levels of P4501A mRNA expression were naturally induced in feral ...
Cytochromes P450 constitute a superfamily of the phase I enzymes whose primary task is the detoxific...
Ethoxyresorufin is a classical substrate for vertebrate CYP1A enzymes. In Pterygoplichthys sp. (Lori...
A 2,037 bp CYP1A1 cDNA (GenBank AF072899) was cloned through screening of a lambda ZipLox cDNA libra...
A 2,037 bp CYP1A1 cDNA (GenBank AF072899) was cloned through screening of a λZipLox cDNA library con...
In this study, feral leaping mullet (Liza saliens) liver microsomal 7-ethoxyresorufin O-deethylase (...
The purpose of this study was to compare xenobiotic CYP1A induction in liver, gills, and excretory k...
Induction of cytochrome P4501A CYP1A in cultured cells can be used to determine the induction potenc...
Content of cytochromes b(5) and P-450, and activities of NADPH-cytochrome c (P-450) reductase (NCR) ...
Hepatic monooxy genase activities were studied in microsomal fractions from two species of freshwate...
In this study, feral leaping mullet (Liza saliens) liver cytosolic glutathione S-transferases (GSTs)...
CYP1A is known to play important roles in the metabolism, detoxification and bioactivation of carcin...
CYP1A is known to play important roles in the metabolism, detoxification and bioactivation of carcin...
NADPH-cytochrome P450 reductase was purified to electrophoretic homogeneity from detergent-solubiliz...
In this study, CYP2B-immunoreactive protein was purified to electrophoretic homogeneity from the liv...
In this study, we examined whether levels of P4501A mRNA expression were naturally induced in feral ...
Cytochromes P450 constitute a superfamily of the phase I enzymes whose primary task is the detoxific...
Ethoxyresorufin is a classical substrate for vertebrate CYP1A enzymes. In Pterygoplichthys sp. (Lori...
A 2,037 bp CYP1A1 cDNA (GenBank AF072899) was cloned through screening of a lambda ZipLox cDNA libra...
A 2,037 bp CYP1A1 cDNA (GenBank AF072899) was cloned through screening of a λZipLox cDNA library con...
In this study, feral leaping mullet (Liza saliens) liver microsomal 7-ethoxyresorufin O-deethylase (...
The purpose of this study was to compare xenobiotic CYP1A induction in liver, gills, and excretory k...
Induction of cytochrome P4501A CYP1A in cultured cells can be used to determine the induction potenc...
Content of cytochromes b(5) and P-450, and activities of NADPH-cytochrome c (P-450) reductase (NCR) ...
Hepatic monooxy genase activities were studied in microsomal fractions from two species of freshwate...
In this study, feral leaping mullet (Liza saliens) liver cytosolic glutathione S-transferases (GSTs)...