[In vivo selection of fluoroquinolone-resistant Escherichia coli isolates expressing plasmid-mediated quinolone resistance and expanded-spectrum beta-lactamase]
- Poirel, Laurent
- Pitout, Johann D.D.
- Calvo, Lucy
- Rodriguez-Martinez, Jose-Manuel
- Church, Deirdre
- Nordmann, Patrice
Publication date
April 2006
DOI Publisher
American Society for Microbiology Journal
Antimicrobial Agents and ChemotherapyAbstract
Journal Article; Research Support, Non-U.S. Gov't;A ciprofloxacin-resistant Escherichia coli isolate, isolate 1B, was obtained from a urinary specimen of a Canadian patient treated with norfloxacin for infection due to a ciprofloxacin-susceptible isolate, isolate 1A. Both isolates harbored a plasmid-encoded sul1-type integron with qnrA1 and blaVEB-1 genes. Isolate 1B had amino acid substitutions in gyrase and topoisomerase.Ye
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