Haemodialysis patients` quality of life and its relationship with dialysis adequacy and laboratory parameters

Uvod: Hemodializa predstavlja zlati standard zdravljenja pacientov s končno ledvično odpovedjo. Na kakovost življenja hemodializnih pacientov lahko vpliva tudi adekvatnost dializnega zdravljenja in posamezni laboratorijski parametri. Namen zaključnega dela je bil raziskati, kakšna je kakovost življenja hemodializnih pacientov v primerjavi z adekvatnostjo hemodialize in laboratorijskimi parametri. Metode: Izvedena je bila presečno opazovalna raziskava s kvantitativno metodologijo raziskovanja. Podatki so bili zbrani z anketnim vprašalnikom na priložnostnem vzorcu 156 pacientov na hemodializnem zdravljenju. Statistična analiza je bila izvedena s programsko opremo IBM SPSS 23.0 in metodo deskriptivne ter inferenčne statistike. Rezultati: V povprečju imajo hemodializni pacienti dobro kakovost življenja (M = 71,9SD = 12,1). Statistično značilnih razlik v kakovosti življenja glede na spol nismo ugotovili (U = 237,5p = 0,735). Prav tako nismo ugotovili statistično značilne povezave med kakovostjo življenja in adekvatnostjo dializnega zdravljenja (rs = –0,147p = 0,297). Smo pa ugotovili statistično značilno povezavo med kakovostjo življenja in številom let dializnega zdravljenja (rs = –0,313p = 0,025). Prav tako smo ugotovili statistično značilno povezavo med kakovostjo življenja in ravnjo hemoglobina (rs = –0,372p = 0,01) ter albuminov (rs = 0,296p = 0,033). Razprava in sklep: Končna ledvična odpoved vpliva na vsa področja kakovosti življenja hemodializnih pacientov. S socialno podporo in adekvatnim dializnim zdravljenjem pa lahko njihove omejitve zmanjšamo in s tem izboljšamo kakovost življenja.Introduction: Haemodialysis represents the golden standard of end-stage kidney disease treatment. Haemodialysis patients’ quality of life may be affected by haemodialysis adequacy and laboratory parameters. The aim of the study was to explore haemodialysis patients’ quality of life regarding haemodialysis adequacy and laboratory parameters. Methods: A cross-sectional study using quantitative research methodology was used. Data were gathered with a standardised survey questionnaire and a convenience sample of 156 haemodialysis patients. Statistical analysis was carried out using IBM SPSS programme, descriptive and inferential statistics. Results: In average, haemodialysis patients have good quality of life (M = 71.9, SD = 12.1). We found no statistically significant differences of quality of life between male and female haemodialysis patients (U = 237.5, p = 0.735). There were also no statistically significant correlations between overall haemodialysis patients\u27 quality of life and dialysis adequacy (rs = –0.147, p = 0.297). We found a statistically significant correlation between haemodialysis patients\u27 overall quality of life and years of dialysis treatment (rs = –0.313, p = 0.025). We also found a statistically significant correlation between haemodialysis patients\u27 overall quality of life and level of haemoglobin (rs = –0.372, p = 0.01) and serum albumins (rs = 0.296, p = 0.033). Discussion and conclusion: End-stage kidney disease effects many dimensions of haemodialysis patients\u27 quality of life. Social support and adequate dialysis treatment can play an important role in reducing their disease-specific barriers and increasing their quality of life