Add to ORKGThe myeloperoxidase (MPO) and lactoferrin genes are strictly associated to the granulocytic differentiation pathway. Many reports show that immunologic and molecular cell markers, though to be lineage specific, are in fact expressed in cells of different lineages. We have identified lymphoid blast cell populations expressing the MPO gene at the mRNA level, but lacking any detectable MPO protein. We addressed this issue studying the expression of the MPO and lactoferrin genes in extremely homogenous Acute Lymphoblastic Leukemia (ALL) blast cell populations. The study was carried out by solution hybridization of total cellular mRNA extracted from the leukemic populations with an antisense RNA transcribed by riboprobes. Either MPO or lactoferr...
A b s t r a c t To evaluate the frequency and significance of myeloperoxidase positivity in adult ac...
Parallel to fingerprinting of leukemia subclasses by gene expression profiling we propose to fingerp...
This study assesses the value of immunologic and ultrastructural methods in disclosing the lineage c...
The myeloperoxidase (MPO) and lactoferrin genes are strictly associated to the granulocytic differen...
By using a cDNA clone of the myeloperoxidase (MPO) gene, we have studied, by Northern blot analysis,...
The hybridization to a complementary RNA (cRNA) probe both in situ and in solution was used to assay...
In this study, we examined myeloperoxidase (MPO) gene expression in a series of 31 non-infant pro-B ...
In this study, we examined myeloperoxidase (MPO) gene expression in a series of 31 non-infant pro-B ...
The expression of the myeloperoxidase (MPO) gene was studied, by means of Northern blot analysis in ...
The level of expression of the myeloperoxidase gene (MPO), strictly associated with myeloid differen...
On the basis of negativity for myeloperoxidase (MPO) and absence of lineage-associated antigens on t...
Total cellular RNA from a series of leukemic cell populations, both myeloid and lymphoid, as well as...
BACKGROUND: Flow cytometry of lineage markers is useful in the classification of leukemias. Our aim ...
The authors have assayed the level of expression of several cell-cycle related genes in several popu...
CD22, one of the important markers for diagnosing B-lineage acute leukemia, was expressed in mature ...
A b s t r a c t To evaluate the frequency and significance of myeloperoxidase positivity in adult ac...
Parallel to fingerprinting of leukemia subclasses by gene expression profiling we propose to fingerp...
This study assesses the value of immunologic and ultrastructural methods in disclosing the lineage c...
The myeloperoxidase (MPO) and lactoferrin genes are strictly associated to the granulocytic differen...
By using a cDNA clone of the myeloperoxidase (MPO) gene, we have studied, by Northern blot analysis,...
The hybridization to a complementary RNA (cRNA) probe both in situ and in solution was used to assay...
In this study, we examined myeloperoxidase (MPO) gene expression in a series of 31 non-infant pro-B ...
In this study, we examined myeloperoxidase (MPO) gene expression in a series of 31 non-infant pro-B ...
The expression of the myeloperoxidase (MPO) gene was studied, by means of Northern blot analysis in ...
The level of expression of the myeloperoxidase gene (MPO), strictly associated with myeloid differen...
On the basis of negativity for myeloperoxidase (MPO) and absence of lineage-associated antigens on t...
Total cellular RNA from a series of leukemic cell populations, both myeloid and lymphoid, as well as...
BACKGROUND: Flow cytometry of lineage markers is useful in the classification of leukemias. Our aim ...
The authors have assayed the level of expression of several cell-cycle related genes in several popu...
CD22, one of the important markers for diagnosing B-lineage acute leukemia, was expressed in mature ...
A b s t r a c t To evaluate the frequency and significance of myeloperoxidase positivity in adult ac...
Parallel to fingerprinting of leukemia subclasses by gene expression profiling we propose to fingerp...
This study assesses the value of immunologic and ultrastructural methods in disclosing the lineage c...