Effective antiretroviral therapy (ART) has prolonged life expectancy among people living with HIV (PLWH) in most parts of Europe, but as PLWH are ageing, this group is now starting to experience signs of compromised health, with particular concerns around possible increased rates of frailty, falls and fractures. In this thesis I use data from the Pharmacokinetic and Clinical Observations in People Over Fifty (POPPY) study (699 older (≥50 years) PLWH, 374 younger (<50 years) PLWH and 304 HIV-negative controls (≥50 years)) to examine some of the challenges of ageing in PLWH in England and Ireland. In particular, I investigate frailty, falls, bone mineral density (BMD), fractures and fracture (hip and major-osteoporotic) risk among PLWH and HI...
OBJECTIVES: Some evidence suggests that HIV infection is associated with premature frailty-a syndrom...
BACKGROUND: Frailty is associated with mortality and morbidity in the general geriatric population, ...
BACKGROUND: Frailty and falls occur commonly and prematurely in HIV-infected populations. Whether fr...
This paper will update care providers on the clinical and scientific aspects of frailty which affect...
International audienceObjective: The study aims to assess the association between bone mineral densi...
As a result of the successful treatment of HIV over the last four decades, people living with HIV (P...
Between 2006 and 2017, frailty prevalence decreased in HIV-positive individuals aged 50 years but pr...
Background: Contemporary HIV care may reduce frailty in older adults living with HIV (OALWH). Object...
Objectives Recent research has indicated seemingly increased propensity for falls and accelerated bo...
Background: People living with HIV (PLWH) are at higher risk of reduced bone mineral density (BMD...
Objectives: Physical frailty is one of the major concerns among older people living with HIV (PLWH)....
Between 2006 and 2017, frailty prevalence decreased in HIV-positive individuals aged 50 years but pr...
OBJECTIVE: To determine associations between frailty and fracture in women with and without HIV infe...
Standard care for HIV clinical practice has started focusing on age-related problems, but despite th...
Life expectancy of people living with HIV (PLWH) is reaching similar length as in the general popula...
OBJECTIVES: Some evidence suggests that HIV infection is associated with premature frailty-a syndrom...
BACKGROUND: Frailty is associated with mortality and morbidity in the general geriatric population, ...
BACKGROUND: Frailty and falls occur commonly and prematurely in HIV-infected populations. Whether fr...
This paper will update care providers on the clinical and scientific aspects of frailty which affect...
International audienceObjective: The study aims to assess the association between bone mineral densi...
As a result of the successful treatment of HIV over the last four decades, people living with HIV (P...
Between 2006 and 2017, frailty prevalence decreased in HIV-positive individuals aged 50 years but pr...
Background: Contemporary HIV care may reduce frailty in older adults living with HIV (OALWH). Object...
Objectives Recent research has indicated seemingly increased propensity for falls and accelerated bo...
Background: People living with HIV (PLWH) are at higher risk of reduced bone mineral density (BMD...
Objectives: Physical frailty is one of the major concerns among older people living with HIV (PLWH)....
Between 2006 and 2017, frailty prevalence decreased in HIV-positive individuals aged 50 years but pr...
OBJECTIVE: To determine associations between frailty and fracture in women with and without HIV infe...
Standard care for HIV clinical practice has started focusing on age-related problems, but despite th...
Life expectancy of people living with HIV (PLWH) is reaching similar length as in the general popula...
OBJECTIVES: Some evidence suggests that HIV infection is associated with premature frailty-a syndrom...
BACKGROUND: Frailty is associated with mortality and morbidity in the general geriatric population, ...
BACKGROUND: Frailty and falls occur commonly and prematurely in HIV-infected populations. Whether fr...