In the current conditions of rapid digitalization of the worldwide space, taking into account global factors, which are being forced, including such «black swans» as the COVID-19 pandemic, the issues of e-commerce development in the context of certain regions are being activated. The article is aimed at studying and identifying the features and trends of e-commerce development in the Latin American region, a detailed analysis of Brazil, Mexico and Argentina as the largest markets in the region. To achieve this aim, the methods of scientific abstraction, analysis and synthesis, statistical analysis, comparison, structural and logical generalization were used. The article determines that, given the large population of the region with a signif...