Objectives. Design of Experiments (DOE) is a powerful tool for identifying important formulation factors and process parameters in drug design and manufacturing, to ensure certain product specifications. This study aimed at manufacturing curcumin-loaded polycaprolactone nanoparticles (CURC-PCL NP), and used DOE in order to understand how formulation and process variables impact the drug delivery system’s characteristics. Polymeric nanoparticles are a suitable approach for incorporating hydrophobic drugs such as curcumin, in order to maximize the numerous beneficial effects, and to minimize the side effects and shortcomings such as low water-solubility and bioavailability. Material and methods. The CURC-PCL NP were prepared by the solvent d...
Despite the promising biological and antioxidant properties of curcumin, its medical applications ar...
International audienceCurcumin is a natural polyphenolic compound known for its numerous pharmacolog...
The objective of this study was to enhance the solubility and dissolution rate of a poorly water-sol...
Polymer nanoparticles (NPs) have attracted significant interest in the past years for drug delivery ...
Curcumin nanoparticles have been successfully formulated into transdermal patches using combinations...
Copyright © 2015 Ali Mohammad Alizadeh et al. This is an open access article distributed under the C...
Curcumin (CUR) has impressive pharmacologic properties, including cardioprotective, neuroprotective,...
In this work, curcumin (CURC)-encapsulating nanoparticles (NPs), made up of an amphiphilic blend of ...
In this work, curcumin (CURC)-encapsulating nanoparticles (NPs), made up of an amphiphilic blend of ...
In this work, curcumin (CURC)-encapsulating nanoparticles (NPs), made up of an amphiphilic blend of ...
International audienceDespite the promising biological and antioxidant properties of curcumin, its m...
We apply gas–liquid microfluidic reactors containing flow-variable, high-shear “hot spots” to produc...
This study reports scale-up and shelf-stability of curcumin encapsulated poly(lactic acid-co-glycoli...
Curcumin, a yellow polyphenol derived from the turmeric Curcuma longa, has been associated with a di...
Despite the promising biological and antioxidant properties of curcumin, its medical applications ar...
Despite the promising biological and antioxidant properties of curcumin, its medical applications ar...
International audienceCurcumin is a natural polyphenolic compound known for its numerous pharmacolog...
The objective of this study was to enhance the solubility and dissolution rate of a poorly water-sol...
Polymer nanoparticles (NPs) have attracted significant interest in the past years for drug delivery ...
Curcumin nanoparticles have been successfully formulated into transdermal patches using combinations...
Copyright © 2015 Ali Mohammad Alizadeh et al. This is an open access article distributed under the C...
Curcumin (CUR) has impressive pharmacologic properties, including cardioprotective, neuroprotective,...
In this work, curcumin (CURC)-encapsulating nanoparticles (NPs), made up of an amphiphilic blend of ...
In this work, curcumin (CURC)-encapsulating nanoparticles (NPs), made up of an amphiphilic blend of ...
In this work, curcumin (CURC)-encapsulating nanoparticles (NPs), made up of an amphiphilic blend of ...
International audienceDespite the promising biological and antioxidant properties of curcumin, its m...
We apply gas–liquid microfluidic reactors containing flow-variable, high-shear “hot spots” to produc...
This study reports scale-up and shelf-stability of curcumin encapsulated poly(lactic acid-co-glycoli...
Curcumin, a yellow polyphenol derived from the turmeric Curcuma longa, has been associated with a di...
Despite the promising biological and antioxidant properties of curcumin, its medical applications ar...
Despite the promising biological and antioxidant properties of curcumin, its medical applications ar...
International audienceCurcumin is a natural polyphenolic compound known for its numerous pharmacolog...
The objective of this study was to enhance the solubility and dissolution rate of a poorly water-sol...