The use of digital pathology for the histomorphologic profiling of pathological specimens is expanding the precision and specificity of quantitative tissue analysis at an unprecedented scale; thus, enabling the discovery of new and functionally relevant histological features of both predictive and prognostic significance. In this study, we apply quantitative automated image processing and computational methods to profile the subcellular distribution of the multi-functional transcriptional regulator, Kaiso (ZBTB33), in the tumors of a large racially diverse breast cancer cohort from a designated health disparities region in the United States. Multiplex multivariate analysis of the association of Kaiso’s subcellular distribution with other br...
Examining for new BC biomarkers has proven that kallikrein-related peptidase (KLK) family members re...
Liquid biopsy has proven valuable in identifying individual genetic alterations; however, the abilit...
Background: Cell-surface proteins have been widely used as diagnostic and prognostic markers in canc...
Introduction : Exosomes are communication vesicles between tumor cells and immune cells. However, th...
Kaiso is a BTB/POZ transcription factor that is ubiquitously expressed in multiple cell types and fu...
Triple-negative breast cancers (TNBCs) are histologically heterogenic invasive carcinomas of no spec...
Tumors are heterogeneous tissues with different types of cells such as cancer cells, fibroblasts, an...
Tumor-infiltrating lymphocytes (TILs) have been established as a robust prognostic biomarker in brea...
Mouse models of cancer provide a powerful tool for investigating all aspects of cancer biology. In t...
Breast cancer is a heterogeneous disease comprising a variety of entities with various genetic backg...
Background: There is a need to improve prediction of response to chemotherapy in breast cancer in or...
In the United States, 1 in 8 women are diagnosed with breast cancer. Breast tumor heterogeneity is w...
The complex tumor microenvironment can make molecularly subtyping cancer using mRNA expression chall...
BACKGROUND: Cancer patients have highly variable clinical outcomes owing to many factors, among whic...
BACKGROUND: KIAA1199 is a recently identified novel gene that is up-regulated in human cancer with p...
Examining for new BC biomarkers has proven that kallikrein-related peptidase (KLK) family members re...
Liquid biopsy has proven valuable in identifying individual genetic alterations; however, the abilit...
Background: Cell-surface proteins have been widely used as diagnostic and prognostic markers in canc...
Introduction : Exosomes are communication vesicles between tumor cells and immune cells. However, th...
Kaiso is a BTB/POZ transcription factor that is ubiquitously expressed in multiple cell types and fu...
Triple-negative breast cancers (TNBCs) are histologically heterogenic invasive carcinomas of no spec...
Tumors are heterogeneous tissues with different types of cells such as cancer cells, fibroblasts, an...
Tumor-infiltrating lymphocytes (TILs) have been established as a robust prognostic biomarker in brea...
Mouse models of cancer provide a powerful tool for investigating all aspects of cancer biology. In t...
Breast cancer is a heterogeneous disease comprising a variety of entities with various genetic backg...
Background: There is a need to improve prediction of response to chemotherapy in breast cancer in or...
In the United States, 1 in 8 women are diagnosed with breast cancer. Breast tumor heterogeneity is w...
The complex tumor microenvironment can make molecularly subtyping cancer using mRNA expression chall...
BACKGROUND: Cancer patients have highly variable clinical outcomes owing to many factors, among whic...
BACKGROUND: KIAA1199 is a recently identified novel gene that is up-regulated in human cancer with p...
Examining for new BC biomarkers has proven that kallikrein-related peptidase (KLK) family members re...
Liquid biopsy has proven valuable in identifying individual genetic alterations; however, the abilit...
Background: Cell-surface proteins have been widely used as diagnostic and prognostic markers in canc...