Add to ORKGParkinson?s disease (PD) is the second most prevalent neurodegenerative disorder, and it is characterized by the progressive degeneration of the dopaminergic neurons located in the substantia nigra pars compacta, striatum body and brain cortex. Multiple -genetic and environmental- factors contribute to the appearance of PD; however, mitochondrial dysfunction with the decreased capacity to produce ATP and oxidative damage are pathognomonic characteristics always present in the affected brain areas. Mitochondrial dysfunction includes the concomitant reduction in the active respiration sustained by malate-glutamate and in the complex I activity, accompanied by changes in mtNOS biochemical (i.e. mitochondrial NO production) and functional activ...
As neurons are highly energy-demanding cell, increasing evidence suggests that mitochondria play a l...
As neurons are highly energy-demanding cell, increasing evidence suggests that mitochondria play a l...
As neurons are highly energy-demanding cell, increasing evidence suggests that mitochondria play a l...
none4noReviewIn 1979, it was observed that parkinsonism could be induced by a toxin inhibiting mitoc...
Mitochondrial dysfunction that generates oxidative stress contributes to the etiol-ogy of idiopathic...
The cause of neurodegeneration in the substantia nigra of the brains of Parkinson's disease (PD) pat...
The cause of the selective degeneration of nigrostriatal neurons in Parkinson disease (PD) has remai...
The cause of the selective degeneration of nigrostriatal neurons in Parkinson disease (PD) has remai...
The cause of the selective degeneration of nigrostriatal neurons in Parkinson disease (PD) has remai...
[eng] Parkinson's disease (PD) is a common neurodegenerative disorder of unknown cause. For decades,...
As neurons are highly energy-demanding cell, increasing evidence suggests that mitochondria play a l...
Parkinson's disease (PD) is a progressive, neurodegenerative condition that has increasingly been li...
AbstractMutations of mitochondrial DNA (mtDNA) are associated with a wide spectrum of disorders enco...
As neurons are highly energy-demanding cell, increasing evidence suggests that mitochondria play a l...
As neurons are highly energy-demanding cell, increasing evidence suggests that mitochondria play a l...
As neurons are highly energy-demanding cell, increasing evidence suggests that mitochondria play a l...
As neurons are highly energy-demanding cell, increasing evidence suggests that mitochondria play a l...
As neurons are highly energy-demanding cell, increasing evidence suggests that mitochondria play a l...
none4noReviewIn 1979, it was observed that parkinsonism could be induced by a toxin inhibiting mitoc...
Mitochondrial dysfunction that generates oxidative stress contributes to the etiol-ogy of idiopathic...
The cause of neurodegeneration in the substantia nigra of the brains of Parkinson's disease (PD) pat...
The cause of the selective degeneration of nigrostriatal neurons in Parkinson disease (PD) has remai...
The cause of the selective degeneration of nigrostriatal neurons in Parkinson disease (PD) has remai...
The cause of the selective degeneration of nigrostriatal neurons in Parkinson disease (PD) has remai...
[eng] Parkinson's disease (PD) is a common neurodegenerative disorder of unknown cause. For decades,...
As neurons are highly energy-demanding cell, increasing evidence suggests that mitochondria play a l...
Parkinson's disease (PD) is a progressive, neurodegenerative condition that has increasingly been li...
AbstractMutations of mitochondrial DNA (mtDNA) are associated with a wide spectrum of disorders enco...
As neurons are highly energy-demanding cell, increasing evidence suggests that mitochondria play a l...
As neurons are highly energy-demanding cell, increasing evidence suggests that mitochondria play a l...
As neurons are highly energy-demanding cell, increasing evidence suggests that mitochondria play a l...
As neurons are highly energy-demanding cell, increasing evidence suggests that mitochondria play a l...
As neurons are highly energy-demanding cell, increasing evidence suggests that mitochondria play a l...