CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation

Gentaro Izumi
Hideki Nakano
Keiko Nakano
Gregory S. Whitehead
Sara A. Grimm
Michael B. Fessler
Peer W. Karmaus
Donald N. Cook

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Publication date

August 2021

DOI

10.1038/s41467-021-25307-x

Publisher

Springer Science and Business Media LLC

Journal

Nature Communications

Abstract

Dendritic cells in the lung may be specialised to mediate specific types of immune function. Here the authors show that subpopulations of mouse CD11b+ lung DC at different stages of maturation and phenotype can promote Th17 or Th2 CD4+ T cell differentiation

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CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation

Abstract

Extracted data

CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation

Abstract

Extracted data

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