Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children
- Noam D. Beckmann
- Phillip H. Comella
- Esther Cheng
- Lauren Lepow
- Aviva G. Beckmann
- Scott R. Tyler
- Konstantinos Mouskas
- Nicole W. Simons
- Gabriel E. Hoffman
- Nancy J. Francoeur
- Diane Marie Del Valle
- Gurpawan Kang
- Anh Do
- Emily Moya
- Lillian Wilkins
- Jessica Le Berichel
- Christie Chang
- Robert Marvin
- Sharlene Calorossi
- Alona Lansky
- Laura Walker
- Nancy Yi
- Alex Yu
- Jonathan Chung
- Matthew Hartnett
- Melody Eaton
- Sandra Hatem
- Hajra Jamal
- Alara Akyatan
- Alexandra Tabachnikova
- Lora E. Liharska
- Liam Cotter
- Brian Fennessy
- Akhil Vaid
- Guillermo Barturen
- Hardik Shah
- Ying-chih Wang
- Shwetha Hara Sridhar
- Juan Soto
- Swaroop Bose
- Kent Madrid
- Ethan Ellis
- Elyze Merzier
- Konstantinos Vlachos
- Nataly Fishman
- Manying Tin
- Melissa Smith
- Hui Xie
- Manishkumar Patel
- Kai Nie
- Kimberly Argueta
- Jocelyn Harris
- Neha Karekar
- Craig Batchelor
- Jose Lacunza
- Mahlet Yishak
- Kevin Tuballes
- Ieisha Scott
- Arvind Kumar
- Suraj Jaladanki
- Charuta Agashe
- Ryan Thompson
- Evan Clark
- Bojan Losic
- Lauren Peters
- The Mount Sinai COVID-19 Biobank Team
- Panagiotis Roussos
- Jun Zhu
- Wenhui Wang
- Andrew Kasarskis
- Benjamin S. Glicksberg
- Girish Nadkarni
- Dusan Bogunovic
- Cordelia Elaiho
- Sandeep Gangadharan
- George Ofori-Amanfo
- Kasey Alesso-Carra
- Kenan Onel
- Karen M. Wilson
- Carmen Argmann
- Supinda Bunyavanich
- Marta E. Alarcón-Riquelme
- Thomas U. Marron
- Adeeb Rahman
- Seunghee Kim-Schulze
- Sacha Gnjatic
- Bruce D. Gelb
- Miriam Merad
- Robert Sebra
- Eric E. Schadt
- Alexander W. Charney
Publication date
August 2021
DOI Publisher
Springer Science and Business Media LLC Journal
Nature CommunicationsAbstract
Multisystem inflammatory syndrome in children (MIS-C) onsets in COVID-19 patients with manifestations similar to Kawasaki disease (KD). Here the author probe the peripheral blood transcriptome of MIS-C patients to find signatures related to natural killer (NK) cell activation and CD8+ T cell exhaustion that are shared with KD patients
Add to ORKG