Diabetes mellitus is a heterogeneous disease characterized by hyperglycemia due to impaired insulin secretion and/or action. All diabetes types have a strong genetic component. The most frequent forms, type 1 diabetes (T1D), type 2 diabetes (T2D) and gestational diabetes mellitus (GDM), are multifactorial syndromes associated with several genes' effects together with environmental factors. Conversely, rare forms, neonatal diabetes mellitus (NDM) and maturity onset diabetes of the young (MODY), are caused by mutations in single genes. Large scale genome screenings led to the identification of hundreds of putative causative genes for multigenic diabetes, but all the loci identified so far explain only a small proportion of heritability. Never...
Diabetes Mellitus (DM) is a complex disease with a significant impact in today’s world. Studies have...
Type 2 diabetes (T2DM) is a serious disease with severe complications. Around one in 10 people alive...
Type 2 diabetes (T2D) is a complex disease that is caused by a complex interplay between genetic, ep...
Diabetes mellitus is a heterogeneous disease characterized by hyperglycemia due to impaired insulin ...
Diabetes mellitus is a heterogeneous disease characterized by hyperglycemia due to impaired insulin ...
Inheritance plays an important role in the cause of diabetes. A considerable amount of research is d...
Genes play an important role in the development of diabetes mellitus. Putative susceptibility genes ...
Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in i...
The identification and functional characterisation of genetic variants that either cause or predispo...
Diabetes mellitus is a heterogeneous disease characterized with a disorder of glucose metabolism whi...
Although non-insulin-dependent diabetes mellitus (NIDDM) has been widely thought to be an inheritabl...
Individuals with higher-than-normal blood sugar levels used to be diagnosed as having either type 1 ...
Diabetes affects millions of people worldwide, and its chronic complications are a leading cause of ...
This review focuses on gene discovery strategies used to identify monogenic forms of diabetes caused...
The aetiology of type 2 diabetes is complex with both genetic and environmental factors playing a ro...
Diabetes Mellitus (DM) is a complex disease with a significant impact in today’s world. Studies have...
Type 2 diabetes (T2DM) is a serious disease with severe complications. Around one in 10 people alive...
Type 2 diabetes (T2D) is a complex disease that is caused by a complex interplay between genetic, ep...
Diabetes mellitus is a heterogeneous disease characterized by hyperglycemia due to impaired insulin ...
Diabetes mellitus is a heterogeneous disease characterized by hyperglycemia due to impaired insulin ...
Inheritance plays an important role in the cause of diabetes. A considerable amount of research is d...
Genes play an important role in the development of diabetes mellitus. Putative susceptibility genes ...
Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in i...
The identification and functional characterisation of genetic variants that either cause or predispo...
Diabetes mellitus is a heterogeneous disease characterized with a disorder of glucose metabolism whi...
Although non-insulin-dependent diabetes mellitus (NIDDM) has been widely thought to be an inheritabl...
Individuals with higher-than-normal blood sugar levels used to be diagnosed as having either type 1 ...
Diabetes affects millions of people worldwide, and its chronic complications are a leading cause of ...
This review focuses on gene discovery strategies used to identify monogenic forms of diabetes caused...
The aetiology of type 2 diabetes is complex with both genetic and environmental factors playing a ro...
Diabetes Mellitus (DM) is a complex disease with a significant impact in today’s world. Studies have...
Type 2 diabetes (T2DM) is a serious disease with severe complications. Around one in 10 people alive...
Type 2 diabetes (T2D) is a complex disease that is caused by a complex interplay between genetic, ep...