A coplanar waveguide system for drug delivery mediated by nanoelectroporation: an experimental and numerical study

Nanosecond pulsed electric fields (nsPEFs) can interact with lipid vesicles, that are primary drug delivery nanocarriers activated by external signals. In this work, authors propose a new setup of an experimental bench suitable for nsPEFs exposure of liposome nanosystems, compliant with the wideband requirements for nanosecond pulses. A multiphysics modelling able to predict liposome poration is proposed to define the characteristics of signals to be used in experiments