Which patients discontinue? Issues on Levodopa/carbidopa intestinal gel treatment. Italian multicentre survey of 905 patients with longterm follow-up
- Sensi M.
- Cossu G.
- Mancini F.
- Pilleri M.
- Zibetti M.
- Modugno N.
- Quatrale R.
- Tamma F.
- Antonini A.
- Aguggia M.
- Amboni M.
- Arca R.
- Bartolomei L.
- Bonetto N.
- Calandra-Buonaura G.
- Bove F.
- Calandrella D.
- Canesi M.
- Cannas A.
- Capecci M.
- Caputo E.
- Ceravolo M. G.
- Ceravolo R.
- Cerrone G.
- Coletti Moja M.
- Comi C.
- Cortelli P.
- D'Antonio P.
- Dematteis F.
- Di Lazzaro V.
- Eleopra R.
- Fabbrini G.
- Fichera M.
- Grassi E.
- Guido M.
- Gusmaroli G.
- Latorre A.
- Malaguti M. C.
- Marano M.
- Marano P.
- Marconi R.
- Mazzucchi S.
- Meco G.
- Minafra B.
- Morgante F.
- Pacchetti C.
- Pierantozzi M.
- Pontieri F. E.
- Riboldazzi G.
- Ricchi V.
- Ricchieri G.
- Rinaldo S.
- Rispoli V.
- Rossi S.
- Rubino A.
- Russo A.
- Saddi M. V.
- Stefani A.
- Simoni S.
- Solla P.
- Tambasco N.
- Tamburin S.
- Tessitore A.
- Torre E.
- Ulivelli M.
- Vita M. Gi
- Volonté M. A.
- on behalf of the
- ITALIAN LEVODOPA CARBIDOPA INTESTINAL GEL WORKING GROUP
DOIAbstract
Objectives: To report the results of a national survey aimed at quantifying the current level of diffusion of Levodopa/carbidopa intestinal gel (LCIG) in Italy. Methods: Sixty Parkinson's Disease (PD) specialists in Italy were invited to complete a survey covering issues on clinical and practical aspects of LCIG therapy. Results: Clinical features of 905 patients were collected retrospectively. The majority of centres reported the use of a multidisciplinary team, biochemistry testing, neurophysiological and neuropsychological tests before and after treatment, in addition to caregivers' training and patient's follow as outpatients. Most centres (60%) used internal guidelines for patient selection. The overall rate of adverse events was 5...
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