Doping Liquid Argon (LAr) with Xenon is a well known technique to shift the light emitted by Argon (128 nm) to a longer wavelength to ease its detection. The largest Xenon doping test ever performed in a LArTPC was carried out in ProtoDUNE Single Phase (ProtoDUNE-SP) at the CERN Neutrino Platform. From February to May 2020, a gradually increasing amount of Xenon was injected to compensate for the light loss due to air contamination. The response of such a large TPC (770 t of Liquid Argon and 440 t of fiducial mass) has been studied using the ProtoDUNE Photon Detection System (PDS) and a dedicated setup installed before the run. With the first, it was possible to study the total light detected in the system as a function of the xenon concen...