The Roles of Nanoparticle in the Treatment and Diagnosis of Ovarian Cancer

Ovarian cancer is the most common type of cancer worldwide among women, and it is usually diagnosed at an advanced stage. The initial treatment for ovarian cancer is surgical debulking, but this is only effective in the treatment of early stage disease. Surgery alone is insufficient for treatment of advanced disease and systemic therapies, in particular chemotherapies, are indicated. The main aim of this book chapter is to review the role of nano-therapy in treatment of advance ovarian cancer, in comparison to the use of traditional chemotherapies. Nano-therapies are thought to have advantages in terms of improving drug stability in the human body, chemotherapy toxicity profile, and drug delivery to the target cells thus enhancing drug penetration into the cancer cells. This book chapter also covers the development of nano-therapy and also the type of potential cargos. In summary, the types of nanocarrier, and their roles ovarian cancer diagnosis and treatment will be discussed