Facile synthesis of Pd nanoparticles supported on a novel Schiff base modified chitosan-kaolin: Antibacterial and catalytic activities in Sonogashira coupling reaction

*Baran, Talat ( Aksaray, Yazar ) *Yılmaz Baran, Nuray ( Aksaray, Yazar )The present work studies the Sonogashira coupling reaction (SCR) between aryl halides and acetylenes under aerobic conditions using the catalytic complex of Pd nanoparticles (NPs) supported on a novel Schiff base modified chitosan-kaolin (Pd NPs@CS-Kao) in ethanol solvent. The prepared catalyst was characterized by TEM, SEM, FT-IR, XRD, EDS, XPS, elemental mapping, and Raman analyses. The products were formed in high yields. At the end of the reaction, Pd NPs@CS-Kao can be filtered and reused for five consecutive cycles. The advantages of this catalytic process include simple methodology, high yields, and easy work-up. In addition, Pd NPs@CS-Kao exhibited effective antibacterial performance against E. coli gram-negative bacteria