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Not AvailableMarine secondary metabolites (MSM) from macro algae were incorporated into four experimental feeds for juvenile shrimp (Penaeus monodon) as follows: 1.0% Hypnea musciformis extract (diet 1); 0.1% H. musciformis extract (diet 2); 1.0% H. musciformis extract with 500 mg Ulva fasciata extract and 50 mg of the antibiotic levamisole (diet 3); 1.0% H. musciformis with 500 mg U. fasciata per kg body weight (diet 4). Diet 3 enhanced bacterial clearance to 99.69% in the hemolymph of shrimp challenged with Vibrio alginolyticus and Vibrio fischeri,significantlyhigherthanclearanceratesinall other treatments and the unmedicated control. Results suggest that feed containing MSM is a good alternative to application of antibiotics in controlling bacterial diseases in shrimpNot Availabl