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Not AvailableSecondary metabolites of the marine sponges Acanthella elongata, Axinella donnani, Callyspongia diffusa, Callyspongia subarmigera, and Echinodictyum gorgonoides were collected from fishing nets and their in vitro antibacterial properties against eight virulent marine fish pathogens were studied at incubation temperatures of 20°C and 30°C. Crude methanol extracts of the tested sponges showed species-specific antibacterial activity. The most active species was A. elongata which inhibited 100% and 87.5% of the tested bacterial isolates at 20°C and 30°C respectively. Callyspongia subarmigera was the least active as it inhibited only 62.5% and 50% of the tested bacteria at those temperatures. Results suggest that fractionation and purification of the crude methanol extract of A. elongata has potential in the development of novel antibiotic substances for managing common bacterial diseases in aquaculture.Not Availabl