The paper suggests amethodology for predicting next-year seasonal pollen index (SPI, a sumof daily-mean pollen concentrations)over large regions and demonstrates its performance for birch in Northern andNorth-Eastern Europe. Astatistical model is constructed using meteorological, geophysical and biological characteristics of the previous year).A cluster analysis of multi-annual data of European Aeroallergen Network (EAN) revealed several large regions inEurope, where the observed SPI exhibits similar patterns of the multi-annual variability.We built the model for thenorthern cluster of stations, which covers Finland, Sweden, Baltic States, part of Belarus, and, probably, Russia andNorway,where the lack of data did not allow for conclusive a...