Espectroscopia de impedancia eléctrica de alta frecuencial para la caracterización de tejidos biológicos

Electrical impedance spectroscopy (EIS) is a measurement technique that provides information on the electrical characteristics of a material, that helping these to know the composition of any material in a non-destructive way. Regarding structured biological tissues (cellular tissues), EIS opens the possibility of studying the extracellular and intracellular mediums as well as the cell membrane, making it possible to characterize different tissues, which opens the possibility of differentiating pathological tissues if their electrical characteristics are affected. The objective of this work is to develop a completely differential analogic front-end, both in generation and detection, for measuring the impedance of different tissues with the Analog Discovery 2, capable of signal generation and acquiring up to 10 MHz. The target application is the detection of skin lesions early. In the future, it is intended to study diabetic patients. The tasks include: -Analysis, design and implementation of fully differential circuits. -Experimental verification (with known impedances) and validation. -Compare the performance of different digital techniques to estimate the performance of the impedance (FFT, digital demodulation, synchronous sampling). -Programming of a suitable user interface (C++, Python and LabView are possible platforms)