The invention relates to neuroprotective, antioxidant quinolylnitrones to which the blood- brain barrier is highly permeable, as potential drugs for the treatment of a cerebral stroke or ischaemia, Alzheimer's and Parkinson's disease and amyotrophic lateral sclerosis.Peer reviewedIsquaemia Biotech S.L., Fundación para la Investigación Biomédica del Hhospital Ramón y Cajal, Consejo Superior de Investigaciones Científicas (España)A1 Solicitud de patente con informe sobre el estado de la técnic
Stroke can be defined as a loss of brain function due to a disturbance of the blood flow. There are ...
Neuroprotection seeks to restrict injury to the brain parenchyma following an ischaemic insult by pr...
Neurodegenerative processes of the central nervous system are an important socially significant prob...
We describe herein the synthesis and neuroprotective capacity of an array of 31 compounds comprising...
Cerebrovascular diseases such as ischemic stroke are known to exacerbate dementia caused by neurodeg...
Cerebrovascular diseases such as ischemic stroke are known to exacerbate dementia caused by neurodeg...
We describe herein the synthesis and neuroprotective capacity of an array of 31 compounds comprising...
In our search for new neuroprotective agents for stroke therapy to improve the pharmacological profi...
We describe here the preparation, neuroprotective analysis, and antioxidant capacity of 11 novel qui...
This study describes CholesteroNitrone <b>2</b> as an antioxidant and neuroprotective agent against ...
We describe the development of quinolylnitrones (QNs) as multifunctional ligands inhibiting cholines...
We describe here the preparation, neuroprotective analysis, and antioxidant capacity of 11 novel qui...
This study describes CholesteroNitrone 2 as an antioxidant and neuroprotective agent against ischemi...
The recent advances of tetramethylpyrazine nitrones and quinolylnitrones for the treatment of stroke...
Oxidative stress is one of the main pathogenic factors of neuron damage in neurodegenerative process...
Stroke can be defined as a loss of brain function due to a disturbance of the blood flow. There are ...
Neuroprotection seeks to restrict injury to the brain parenchyma following an ischaemic insult by pr...
Neurodegenerative processes of the central nervous system are an important socially significant prob...
We describe herein the synthesis and neuroprotective capacity of an array of 31 compounds comprising...
Cerebrovascular diseases such as ischemic stroke are known to exacerbate dementia caused by neurodeg...
Cerebrovascular diseases such as ischemic stroke are known to exacerbate dementia caused by neurodeg...
We describe herein the synthesis and neuroprotective capacity of an array of 31 compounds comprising...
In our search for new neuroprotective agents for stroke therapy to improve the pharmacological profi...
We describe here the preparation, neuroprotective analysis, and antioxidant capacity of 11 novel qui...
This study describes CholesteroNitrone <b>2</b> as an antioxidant and neuroprotective agent against ...
We describe the development of quinolylnitrones (QNs) as multifunctional ligands inhibiting cholines...
We describe here the preparation, neuroprotective analysis, and antioxidant capacity of 11 novel qui...
This study describes CholesteroNitrone 2 as an antioxidant and neuroprotective agent against ischemi...
The recent advances of tetramethylpyrazine nitrones and quinolylnitrones for the treatment of stroke...
Oxidative stress is one of the main pathogenic factors of neuron damage in neurodegenerative process...
Stroke can be defined as a loss of brain function due to a disturbance of the blood flow. There are ...
Neuroprotection seeks to restrict injury to the brain parenchyma following an ischaemic insult by pr...
Neurodegenerative processes of the central nervous system are an important socially significant prob...