Surgical Outcomes of Trabeculectomy in Uveitic Glaucoma: A Long-Term, Single-Center, Retrospective Case-Control Study

Purpose. To evaluate the long-term outcomes of trabeculectomy with mitomycin C (MMC-TLE) in patients with uveitic glaucoma (UG). Patients and Methods. This was a retrospective, nonrandomized case series study. MMC-TLE was performed on 50 eyes with UG between February 2001 and January 2015 at Hokkaido University Hospital. Age- and sex-matched patients with primary open angle glaucoma (POAG) who underwent MMC-TLE were matched by age and sex and enrolled as controls. Surgical success was defined as an intraocular pressure (IOP) less than 18 or 15 mmHg. The Kaplan-Meier survival curves for surgical failure were analyzed. Results. The mean preoperative IOP in UG and POAG was 27.6 +/- 10.6 and 18.0 +/- 4.5 mmHg, respectively. After the surgery, the mean IOP in UG and POAG was reduced to 11.7 +/- 4.2 and 12.2 +/- 3.8 mmHg at 12 months, 11.9 +/- 7.0 and 12.1 +/- 3.1 mmHg at 36 months, and 13.0 +/- 5.2 and 10.6 +/- 1.2 mmHg at 120 months, respectively. The success rates (IOP 20%) in UG and POAG were 91.7% and 88.0% at 12 months, 82.2% and 75.6% at 36 months, and 66.5% and 61.8% at 120 months, respectively. The success rates (IOP