Treatment of Bovine Papilloma

In this study (35) cows suffering from bovine papilloma were subjected for three different types of treatments; The First group involved 15 animals treated with autogenous vaccine. The Second group involved 10 animals treated with prepared cell culture vaccine .While the third group involved 10 cows treated with virulent local Newcastle disease virus. In the First two groups the warts were surgically removed from cows showing lump lesions on skin of abdomen, neck and udder, and transferred aseptically to laboratory by using transport media. Treatment of cows in the first group involved preparation of autogenous formalin (0.5%) in activated vaccine. Vaccination of these animals result in regression of the warts started after 2 or 3 weeks and complete disappearance of the warts after 30-60 days with a mean duration of 44.9 days. Treatment of the second group involved preparation of papilloma cell culture inactivated vaccine 0.5% formalin from 3 papilloma cases. The response of these vaccinated cows result in regression of the warts lesions started after 2 or 3 weeks post the first vaccinal dose and complete disappearance of the warts after 30-60 days, with mean 43.8 days. Treatment of the third group involved using of virulent NDV by subcutaneous injection and infiltration around the warts. Results showed successful regression of warts within a shorter period with mean of 30.1 days compared to treatment with autogenous and cell culture vaccine, with complete regression of the warts within 15-28 days