The explosive development of next-generation sequencing-based technologies has allowed us to take an unprecedented look at many molecular signatures of the non-coding genome. In particular, the ChIP-seq (Chromatin ImmunoPrecipitation followed by sequencing) technique is now very commonly used to assess the proteins associated with different non-coding DNA regions genome-wide. While the analysis of such data related to transcription factor binding is relatively straightforward, many modified histone variants, such as H3K27me3, are very important for the process of gene regulation but are very difficult to interpret. We propose a novel method, called HERON (HiddEn MaRkov mOdel based peak calliNg), for genome-wide data analysis that is able to...
Genome-wide profiling of DNA-binding proteins using ChIP-Seq has emerged as an alternative to ChIP-c...
BACKGROUND: ChIP-seq has become a routine method for interrogating the genome-wide distribution of v...
We propose a unified framework for the analysis of chromatin (Ch) immunoprecipitation (IP) microarra...
<div><p>Next-generation sequencing (NGS) technologies have matured considerably since their introduc...
The Human Genome Project has been completed in 2003, with the sequencing of the human genome. In the...
Gene expression is the process of selectively reading genetic information and it describes a life-es...
International audienceBACKGROUND: Chromatin immunoprecipitation combined with massive parallel seque...
Used to analyze protein interactions with DNA, Chromatin Immunoprecipitation sequencing (ChIP-seq) u...
On benefit of the rapid growth of ultra-high-throughput sequencing technologies in recent years, ChI...
Background: High-throughput sequencing technology has become popular and widely used to study protei...
Motivation: Chromatin structure, including post-translational modifications of histones, regulates g...
Motivation: Chromatin immunoprecipitation (ChIP) experiments followed by array hybridization, or ChI...
Chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-Seq) is a powerful t...
Abstract Background Correctly identifying genomic regions enriched with histone modifications and tr...
Coupling chromatin immunoprecipitation (ChIP) with recently developed massively parallel sequencing ...
Genome-wide profiling of DNA-binding proteins using ChIP-Seq has emerged as an alternative to ChIP-c...
BACKGROUND: ChIP-seq has become a routine method for interrogating the genome-wide distribution of v...
We propose a unified framework for the analysis of chromatin (Ch) immunoprecipitation (IP) microarra...
<div><p>Next-generation sequencing (NGS) technologies have matured considerably since their introduc...
The Human Genome Project has been completed in 2003, with the sequencing of the human genome. In the...
Gene expression is the process of selectively reading genetic information and it describes a life-es...
International audienceBACKGROUND: Chromatin immunoprecipitation combined with massive parallel seque...
Used to analyze protein interactions with DNA, Chromatin Immunoprecipitation sequencing (ChIP-seq) u...
On benefit of the rapid growth of ultra-high-throughput sequencing technologies in recent years, ChI...
Background: High-throughput sequencing technology has become popular and widely used to study protei...
Motivation: Chromatin structure, including post-translational modifications of histones, regulates g...
Motivation: Chromatin immunoprecipitation (ChIP) experiments followed by array hybridization, or ChI...
Chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-Seq) is a powerful t...
Abstract Background Correctly identifying genomic regions enriched with histone modifications and tr...
Coupling chromatin immunoprecipitation (ChIP) with recently developed massively parallel sequencing ...
Genome-wide profiling of DNA-binding proteins using ChIP-Seq has emerged as an alternative to ChIP-c...
BACKGROUND: ChIP-seq has become a routine method for interrogating the genome-wide distribution of v...
We propose a unified framework for the analysis of chromatin (Ch) immunoprecipitation (IP) microarra...