Study of the interaction of selected pharmaceuticals with microplastics

The bachelor thesis aims to study the interaction of selected pharmaceuticals from the group of analgesics and antibiotics with microplastics. The analysis was conducted in the mid-infrared region, which is used to identify chemical structure of the substances. Fourier transform infrared spectroscopy was used as an analytical method. The samples were subjected to technique attenuated total reflection. Ibuprofen and trimethoprim were chosen as analytes due to their common usage in the population. Sorption of pharmaceuticals was undergoing on polyhydroxybutyrate, which is a kind of biodegradable plastics and polyethene terephthalate, which is synthetic. Measured results showed that for the study of interaction with pharmaceuticals, it is more suitable to use biodegradable plastic polyhydroxybutyrate than polyethene terephthalate because of its better results. Infrared spectra output is very influenced by a selection of a solvent